Results 81 to 90 of about 995,892 (303)

Nano‐Gs‐Protein Peptidomimetika: Rationales Design von Peptiden, die vom C‐Terminus von Gα abgeleitet sind und Schlüsselkomponenten der Gs‐β2AR‐Wechselwirkungen nachahmen

open access: yesAngewandte Chemie, EarlyView.
G Protein‐gekoppelte Rezeptoren (GPCRs) sind wichtige therapeutische Zielstrukturen. Die Modulation der GPCR‐Aktivität über intrazelluläre Bindungsstellen gewinnt zunehmend an Bedeutung. Ein strukturell und computergestützter Ansatz ermöglichte die Entwicklung kleiner, vom G Protein abgeleiteter Peptidomimetika, die gezielt an die intrazelluläre ...
Phuong Thu Tran   +11 more
wiley   +1 more source

Sustainability of public debt: Some theoretical considerations [PDF]

open access: yes
This paper elaborates on the relationship between sustainability of public debt and the debt to GDP ratio in case the interest rate on public debt exceeds the growth rate of GDP. When the primary surplus relative to GDP positively reacts to a higher debt
Alfred Greiner
core  

Nano‐Gs Protein Peptidomimetics: Rational Design of Gα C‐Terminus‐Derived Peptides Mimicking Key Components of Gs‐β2AR Interactions

open access: yesAngewandte Chemie International Edition, EarlyView.
G protein‐coupled receptors (GPCRs) are major therapeutic targets. Modulating GPCR activity through intracellular sites is evolving. A structure‐ and computation‐assisted approach generated small G protein‐derived peptidomimetics targeting the intracellular binding crevice of the β2 adrenergic receptor mimicking features of the full G protein.
Phuong Thu Tran   +11 more
wiley   +1 more source

Dynamics of Microtubule Growth and Catastrophe [PDF]

open access: yes, 2007
We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii ...
Antal, T.   +4 more
core   +1 more source

Combined Gravimetric, Electrochemical, and Computational Research on Benzothiophene Derivatives as Effective Corrosion Inhibitors for Mild Steel

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Four benzothiophenes, thianaphthene (BT‐1), 3‐bromothianaphthene (BT‐2), benzo[b]thiophene‐2‐carboxaldehyde (BT‐3), and benzo[b]thiophene‐2‐carbonitrile (BT‐4), were tested as mild steel corrosion inhibitors in 1‐M HCl. The compounds have the similar benzothiophene core but differ in the substituents bound to the ring.
Nhlanhla G. Chirwa   +3 more
wiley   +1 more source

The Trade Potential of Pakistan: An Application of the Gravity Model

open access: yesLahore Journal of Economics
This paper attempts to estimate Pakistan’s trade potential, using the gravity model of trade. Panel data for the period 1981-2005 across 42 countries is employed in the analysis.
Nazia Gul, Hafiz M. Yasin
doaj  

BTUs in GDP [PDF]

open access: yes
Power resources ; Petroleum industry and ...
Michael R. Pakko
core  

Potential for Trouble: The IMF's Estimates of Potential GDP [PDF]

open access: yes, 2016
This issue brief examines the IMF's methodology for estimating potential GDP, and its pitfalls and problems. A number of economists have noted recent problems with overestimates of actual GDP in recent years in Greece, and the IMF's own research has ...
David Rosnick
core  

Socioenvironmental implications of Jatropha curcas cultivation for biodiesel supply in postmining communities

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract The long‐term viability of Jatropha curcas as a biodiesel feedstock has been widely debated. Many early initiatives failed to deliver consistent economic returns despite promising environmental attributes. This study re‐evaluated J. curcas‐based systems within an integrated environmental–economic framework, focusing on their potential role in ...
Eduardo Sansão Sozinho Maurício   +3 more
wiley   +1 more source

Influence of corruption on economic growth rate and foreign investments

open access: yes, 2007
In order to investigate whether government regulations against corruption can affect the economic growth of a country, we analyze the dependence between Gross Domestic Product (GDP) per capita growth rates and changes in the Corruption Perceptions Index (
Boris Podobnik   +10 more
core   +1 more source

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