Results 81 to 90 of about 16,734 (227)

Fully integrated Monte Carlo simulation for evaluating radiation induced DNA damage and subsequent repair using Geant4-DNA

Scientific Reports, 2020
Ionising radiation induced DNA damage and subsequent biological responses to it depend on the radiation’s track-structure and its energy loss distribution pattern. To investigate the underlying biological mechanisms involved in such complex system, there
D. Sakata, O. Belov, M. Bordage, D. Emfietzoglou, S. Guatelli, T. Inaniwa, V. Ivanchenko, M. Karamitros, I. Kyriakou, Nathanael Lampe, I. Petrović, A. Ristic-Fira, W. Shin, S. Incerti   +13 more
semanticscholar   +1 more source

A multidisciplinary experimental and methodological investigation of electron and proton minibeams in the framework of the INFN MIRO project

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background The clinical translation of Minibeam RT (MBRT) has recently started thanks to the first human treatments recently performed. However, despite experimental evidence, the impact of the dose distribution parameters involved on the magnitude of the effect itself and the underlying radiobiological mechanisms are still only partially ...
Francesco Romano, Francesca Cella Zanacchi, Esther Ciarrocchi, Gaia Franciosini, Giuliana Milluzzo, Emanuele Scifoni, Anna Vignati, Said Ahmad, Silvia Arezzini, Andrea Attili, Marco Battestini, Jacopo Bernardini, Matteo Bettanin, Alessandra Bisio, Maria Giuseppina Bisogni, Igor Bodrenko, Giulio Bordieri, Valentina Bravatà, Alberto Burattini, Massimo Camarda, Francesco Paolo Cammarata, Simone Capaccioli, Lorenzo Castelli, Andrea Cavalieri, Mariagrazia Celentano, Enrica Chiadroni, Francesco Giuseppe Cordoni, Elena Corvaia, Mario Costa, Alessandro Curcio, Eleonora Da Pozzo, Martina De Felice, Francesca Del Debbio, Francesco D'Errico, Maria Cristina D'Oca, Beatrice D'Orsi, Umberto Deut, Elisabetta Durisi, Maria Evelina Fantacci, Stefano Farina, Giuseppe Felici, Arianna Ferro, Luca Ficcadenti, Antonino Formuso, Giusi Irma Forte, Simona Giordanengo, Alessia Giuliano, Lucia Giuliano, Luca Lanzanò, Stefania Linsalata, Simone Lossano, Margherita Maffei, Michela Marafini, Maurizio Marrale, Maurizio Massa, Luigi Masturzo, Enrico Mazzoni, Mauro Migliorati, Felix Mas Milian, Luigi Minafra, Andrea Moggi, Diango Montalvan Olivares, Marco Montefiori, Matteo Morrocchi, Andrea Mostacci, Franco Mostardi, Chinonso Okpuwe, Fabiola Paiar, Luigi Palumbo, Vincenzo Patera, Jake Harold Pensavalle, Gaia Pucci, Flaminia Quattrini, Alessandra Retico, Valeria Rosso, Giorgio Russo, Roberto Sacchi, Alessio Sarti, Silvia Scalisi, Camilla Scapicchio, Angelo Schiavi, Paolo Stochino, Enrica Strettoi, Francesco Tommasino, Valentina Tozzini, Giacomo Traini, Gabriele Trovato, Alice Usai, Francesco Urso, Fabio Di Martino   +89 more
wiley   +1 more source

Lighting up FLASH and beyond: TLD response across four orders of magnitude in proton dose rate

Medical Physics, Volume 53, Issue 8, August 2026.
ABSTRACT Background Thermoluminescent dosimeters (TLDs) are widely used for proton therapy dosimetry and remote audits. Yet their response under pulsed delivery and the ultrahigh dose rates relevant to proton FLASH remains incompletely characterized.
Fada Guan, Jason Tang, Ally Brookner, Hayden Scott, Ivan Vazquez, Sabrina Campelo, Daniel Liu, Jacob Mathew, Lawrence Bronk, Yuting Li, Paige Taylor   +10 more
wiley   +1 more source

Feasibility of convection‐enhanced delivery of unlabeled 225Ac for glioblastoma: Transport, dosimetry, and clonogenic survival modeling

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Glioblastoma (GB) is an aggressive primary brain tumor with local recurrence rates exceeding 90% and a five‐year survival rate of approximately 5%. Standard treatments such as surgical resection, external beam radiotherapy (EBRT), and chemotherapy often leave residual tumor cells that are resistant to therapy.
Maram El Sabri, Leyla Moghaddasi, Puthenparampil Wilson, Frank Saran, Eva Bezak   +4 more
wiley   +1 more source

The Geant4 Bertini Cascade [PDF]

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2015
One of the medium energy hadron–nucleus interaction models in the Geant4 simulation toolkit is based partly on the Bertini intranuclear cascade model. Since its initial appearance in the toolkit, this model has been largely re-written in order to extend its physics capabilities and to reduce its memory footprint. Physics improvements include extensions
Wright, D.H., Kelsey, M.H.
openaire   +1 more source

Effectiveness of Geant4 in Monte Carlo Simulation Studyofphonon Conduction in Sn Host with Si Nanowire Interface

Annals of West University of Timisoara: Physics, 2019
We have explored the effectiveness of Geant4 by using it to simulate phonon conduction in Sn Host with Si Nanowire Interface. Our Monte Carlo Simulation shows that the effectiveness of the phonon conduction Geant4 simulation increases when the system ...
Iheduru C., Eleruja M. A., Olofinjana B., Awe O. E., Buba A.D.A   +4 more
doaj   +1 more source

Radiobiology studies of gold nanoparticle‐enhanced radiosensitization in proton therapy

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Approximately 50%$\%$ of newly diagnosed cancer patients worldwide receive radiotherapy, most commonly with X‐rays. Proton therapy has emerged as a promising alternative, offering complementary advantages over conventional X‐rays due to its highly localized energy deposition at the Bragg peak, thereby reducing radiation exposure to ...
N. Fuster‐Martínez, D. H. Saucedo‐Cuberes, M. C. Jiménez‐Ramos, D. Esperante, J. M. Espino, J. Fuster, J. F. Belén‐Aguilar, L. González‐López, P. Huertas, S. Jimeno, I. Mingarro, D. Pascual, D. Suárez‐García, M. J. García‐Murria   +13 more
wiley   +1 more source

Scattered Ray Correction for High-Energy X-Ray Nondestructive Testing System for Nuclear Fuel Assemblies Based on MC Method

Journal of Isotopes
High energy X-ray non-destructive testing technology can obtain the internal structure information of the inspected object without destroying it. The multi-rod-beam nature of nuclear fuel assemblies can lead to severe scattering ray effects，which can ...
Zhi ZHONG, Gaokui HE, Xiangyang ZHANG
doaj   +1 more source

An ion treatment planning framework for inclusion of nanodosimetric ionization detail through cluster dose

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Nanodosimetry relates the cumulative or statistical moments of Ionization Detail (ID) with biological endpoints of relevance to cancer radiotherapy using charged particles. This association suggests to develop an additional physics‐detailed layer of modeling that may complement biological modeling and treatment planning.
Simona Facchiano, Ramon Ortiz, Remo Cristoforetti, Naoki D‐Kondo, Oliver Jäkel, Bruce Faddegon, Niklas Wahl   +6 more
wiley   +1 more source

Quantitative Analysis of Transmission XRD Background Based on Monte Carlo Simulation

Yuanzineng kexue jishu
The first prerequisite for obtaining correct information from an X-ray diffraction pattern is to accurately remove the background. The most commonly used method in experiments is direct subtraction, which ignores the absorption of the sample and other ...
YUAN Jingxi, HUANG Ning, HE Ze, PENG Bo, WANG Peng
doaj   +1 more source