Results 51 to 60 of about 707,394 (302)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Utilizing Thermal Energy for Crosslinking Gels: A Novel Rapid Approach
Energies, 2023 A novel route was invented for utilizing thermal energy (at an elevated temperature of 110 ± 2 °C) to synthesize and crosslink gels from resorcinol and formaldehyde without using catalysts or buffers. The outcome gels are identified by various techniques
Ahmed Awadallah-F +1 more
doaj +1 more source
, 2013 This file contains original E-gel images for the manuscript MER-13-0064 1)PVA is labeled as ‘NVI’ 2)Fridge storage is labeled as ‘fresh’ in some E-gels 3)E-gels were reused twice 4)Please refer to Table 2 in the manuscript for detailed experiment setup ...
Natalia V. Ivanova (361995) +3 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Application of a Dopa Derivative for the Formation of Gels in the Presence of Commercial Surfactants
GelsCosmetic formulations are complex mixtures of ingredients that must fulfill several requirements. One of the challenges of the cosmetic industry is to find natural alternatives to replace synthetic polymers, preserving desirable sensory characteristics ...
Sofia Chinelli +3 more
doaj +1 more source
German Journal of Pharmaceuticals and Biomaterials, 2023 Protracted oral Naproxen administration for acute and chronic conditions, such as rheumatoid arthritis treatment, may cause peptic ulcers. The topical application of Naproxen will circumvent this effect.
Sinodukoo Eziuzo Okafo +3 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
, 2012 OBJECTIVES: Application of acidulated phosphate fluoride ( APF) gels has long been considered to cause deterioration of composite surfaces. The aims of this study were to demonstrate that nanocomposite surfaces were not affected by some APF gels and to ...
YEH, SHU-TUAN;WANG, HAO-TING;LIAO, HUA-YANG;CHANG, CHE-CHEN;KAO, HUNG-CHAN;LEE, BOR-SHIUNN +1 more
core +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source