Results 41 to 50 of about 7,234 (285)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

No initial empty CV in clusterless languages [PDF]

open access: yes, 2006
From the inception of strict CV in Lowenstamm (1996) the question of how surface clusters are licensed in Government Phonology has been a contentious one.
Kula, NC
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Proposal for encoding the Mandaic script in the BMP of the UCS [PDF]

open access: yes, 2008
This is a proposal to encode the Mandaic script in the international character encoding standard Unicode. This set of characters was published in Unicode Standard version 6.0 in October 2010.
Everson, Michael
core  

À propos d’une hypothèse sur la forme primitive du type B en amharique [PDF]

open access: yes, 1986
En sémitique, une même racine verbale peut être conjuguée sans gémination, et avec gémination. La première conjugaison correspond à l’action simple, tandis que la seconde exprime l’« intensif ».Dans les langue sémitiques d’Éthiopie, une racine se ...
Lowenstamm, Jean
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Gemination mandibular third molar – A rare case with use of CBCT in diagnosis and treatment planning

open access: yesJournal of Indian Academy of Oral Medicine and Radiology, 2019
It is not uncommon to find dental anomalies in routine practice. Developmental dental anomalies may be seen in tooth number, size, shape, and structure.
Pooja Bhatt   +3 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Language of Latin Curse Tablets from Pannonia: A New Curse Tablet from Aquincum. [PDF]

open access: yes, 2009
Summary: A lead tablet recently discovered in the eastern cemetery of the Aquincum civil town is of much interest. The tablet which can be dated on archaeological grounds to the late 2nd–early 3rd centuries AD seems to be a binding curse of a group of ...
Barta, Andrea
core   +1 more source

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