Results 41 to 50 of about 7,371 (304)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Contemporary Clinical Dentistry, 2012 Gemination and fusion are morphological dental anomalies, characterized by the formation of a clinically wide tooth. Gemination occurs when one tooth bud tries to divide, while fusion occurs if two buds unite.
Vinaya Kumar Kulkarni +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Co-occurrence of gemination and dens invaginatus: a case report
Çukurova Üniversitesi Tıp Fakültesi Dergisi, 2016 Gemination is a developmental anomaly where a single tooth bud attempts to split into two. It is also sometimes called as double tooth or twinning. Dens invaginatus is another developmental anomaly caused due to invagination of a portion of crown.
Sonika Achalli +3 more
doaj +1 more source
À propos d’une hypothèse sur la forme primitive du type B en amharique [PDF]
, 1986 En sémitique, une même racine verbale peut être conjuguée sans gémination, et avec gémination. La première conjugaison correspond à l’action simple, tandis que la seconde exprime l’« intensif ».Dans les langue sémitiques d’Éthiopie, une racine se ...
Lowenstamm, Jean
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Gemination mandibular third molar – A rare case with use of CBCT in diagnosis and treatment planning
Journal of Indian Academy of Oral Medicine and Radiology, 2019 It is not uncommon to find dental anomalies in routine practice. Developmental dental anomalies may be seen in tooth number, size, shape, and structure.
Pooja Bhatt +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
An acoustic investigation of the developmental trajectory of lexical stress contrastivity in Italian [PDF]
, 2016 We examined whether typically developing Italian children exhibit adult-like stress contrastivity for word productions elicited via a picture naming task (n=25 children aged 3\u20135 years and 27 adults).
Arciuli, Joanne, Colombo, Lucia
core +1 more source