Results 71 to 80 of about 7,234 (285)

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Triple tooth in primary dentition: A proposed classification

open access: yesContemporary Clinical Dentistry, 2013
Triple teeth may result from fusion, gemination or concrescence causing transient esthetic and functional problems in primary dentition and retardation or alteration of development and eruption of permanent successors.
Gaddam Shilpa, Sivakumar Nuvvula
doaj   +1 more source

On Characterizing Sanskrit Gemination [PDF]

open access: yes, 2015
In Sanskrit, various intervocalic biconsonantal clusters are affected by gemination, which istypically summarized by phonetic treatises as follows. First, postvocalic consonants followedby another consonant is geminated as in sapta- `seven\u27 > sappta ...
Yasuko Suzuki, 鈴木 保子
core   +1 more source

Set the controls for the heart of the alternation: Dahl’s Law in Kitharaka [PDF]

open access: yes, 2013
This paper looks at Dahl’s Law, a voicing dissimilation process found in a number of Bantu languages, in Kitharaka, and argues that it is best analysed within a framework of minimal (contrastive) feature spe- cifications.
Uffmann, Christian
core   +3 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Multiple dental gemination: a clinical case report

open access: yesRevista Facultad de Odontología Universidad de Antioquia, 2009
Dental gemination and fused teeth are anomalies affecting in shape and number the normal dental formula, interfering with the development of the dentition and occlusion of the growing patient.
Jesús Alberto Hernández-Silva   +2 more
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Vowel duration in stressed position in central & northern varieties of standard Italian [PDF]

open access: yes, 2011
We report the results of a pilot study investigating the effect of 2 regional accents on stressed vowel duration according to word-position and syllable type in Central v. Northern accents of Standard Italian.
Hajek, John, Lee, Wai-Sum, Stevens, Mary
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Vowel duration, compression and lengthening in stressed syllables in Italian [PDF]

open access: yes, 2007
The focus of this study is on temporal organization, specifically of vowel duration, in stressed syllables in (standard) Italian. We investigate possible compression effects on the duration of stressed vowels according to wordposition (final, penult and ...
Hajek, John   +3 more
core   +1 more source

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