Results 31 to 40 of about 83,732 (304)

KAJIAN HISTORIS INTEGRASI POLRI KE DALAM STRUKTUR ABRI 1961-1999

Sejarah dan Budaya: Jurnal Sejarah, Budaya, dan Pengajarannya, 2021
TNI and Polri are state instruments in charge of maintaining the country's defenses. Both are the main pillars in maintaining state security and sovereignty, both for disturbances that come from within and outside.
Galun Eka Gemini
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Canine Fecal Microbiome Dataset: Ultra-deep Multi-platform Sequencing Across Extraction and Library Protocols

Scientific Data
The canine gut microbiome is an important model for microbiome research, yet methodological variation in DNA isolation, library preparation, and sequencing complicates cross-study comparisons.
Balázs Kakuk, Ákos Dörmő, Ahmed Taifi, Tamás Járay, Gábor Kurucsai, Gábor Gulyás, István Prazsák, Zsolt Boldogkői, Dóra Tombácz   +8 more
doaj   +1 more source

Evaluating Machine Translation Models and LLMs for Indonesian–Javanese Translation Across Speech Levels

Journal of Applied Informatics and Computing
Despite being one of the most widely spoken regional languages in Indonesia, Javanese remains underrepresented in modern machine translation systems, particularly with respect to its hierarchical speech-level system.
Mahendra Bayu Prayoga, Bagas Restya Ermawan, Akmal Rafi Fadhillah, Mohammad Nizar Farizi, Ema Utami   +4 more
doaj   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

AI-Driven Clinical Guidance in Necrotizing Enterocolitis: Concordance with European Neonatal Care Standards

Forbes Tıp Dergisi
Objective: Necrotizing enterocolitis (NEC) is a life-threatening emergency in neonatal medicine, especially among premature infants, with high morbidity and mortality. Despite the availability of evidence-based resources such as the European Standards of
Saime SÜNDÜS UYGUN, Mehmet SARIKAYA
doaj   +1 more source

Using traditional methods of hadith verification, modern computer programs, and artificial intelligence in verifying prophetic hadiths - a survey study - [PDF]

مجلة جامعة الأنبار للعلوم الإسلامية
The study addresses a comparison between traditional and modern methodologies in the authentication (takhreej) of Prophetic hadiths, highlighting the advantages and disadvantages of each.
Aisha Amin Abdullah Abd -, Saif Mohammed Stori -, Shihab Ahmed -, Israa Basim Mohammed Abbas -   +3 more
doaj   +1 more source

gemini3d/GEMINI: allow MSYS2 windows to work, bugfix, cleanup

, 2020
for CMake >= 3.15, enforce CMP0094 which greatly improves Python finding allow MS-MPI to work, useful for MSYS2 Gfortran. only directly reference MPI module in the mpimod.f90 (and some unit tests) Now there are four ways to run Gemini on Windows ...
guygrubbs, Michael Hirsch, Ph.D., Matthew D. Zettergren   +2 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source