Results 161 to 170 of about 3,574 (241)

Immunotherapy in advanced gastroesophageal cancers: A meta-analysis of sex-based outcomes in overall survival. [PDF]

Int J Cancer
Masetti M, Petrelli F, Pietrantonio F, Lorenzen S, Leone AG.   +4 more
europepmc   +1 more source

Control of Gemcitabine Activity With Blue and Red Light

Chemistry – A European Journal, EarlyView.
Treating cancer with chemotherapy is generally associated with many side effects, which can be addressed by selectively releasing the desired drugs with visible light. Sixteen new blue light‐activatable cytostatics were introduced, with the gemcitabine derivative exhibiting ideal properties.
Nils F. Kersten, Konstantin L. Stock, Marius Hyprath, Hannah Weisser, Timo Weinrich, Dieter Steinhilber, Alexander Heckel   +6 more
wiley   +1 more source

Sugemalimab plus chemotherapy vs. chemotherapy for treatment of Chinese patients with esophageal squamous cell carcinoma: a cost effectiveness analysis to inform decision making. [PDF]

Front Oncol
Chen Q, Sun Q, Li B.
europepmc   +1 more source

Cyclopropylamine‐Derived Distonic Iminium Radicals: Photoinduced Strategies in Chemo‐ and Stereo‐Selective Synthesis

Chemistry – A European Journal, EarlyView.
Cyclopropylamines have emerged as powerful photocatalytic building blocks. Upon light‐induced single‐electron oxidation, they undergo strain‐release ring opening to generate distonic iminium radicals that enable diverse transformations, including ring‐opening functionalization, formal [3 + 2] cycloadditions, radical cascades, and asymmetric bond ...
Maria Chiara Cabua, Alberto Luridiana, Francesco Secci, Emanuele Cocco   +3 more
wiley   +1 more source

Cost-effectiveness of sugemalimab plus chemotherapy as first-line therapy in advanced gastric cancer and gastroesophageal junction cancer. [PDF]

Ann Med
Zhu J, Li Z, Xu Q.
europepmc   +1 more source

C‐Terminal Functionalization Methods of Amino Acids, Peptides, and Proteins

Chemistry – A European Journal, EarlyView.
C‐terminal functionalization offers powerful routes to peptide and protein diversification, yet epimerization, hydrolysis, and selectivity remain key challenges. This Review surveys enzymatic, decarboxylative, and condensation strategies, highlighting advances toward chemo‐ and regioselective, protecting‐group‐free, atom‐efficient methods applicable to
Jay Hanssens, Mark Lambers, Romano V. A. Orru, Jordy M. Saya   +3 more
wiley   +1 more source

Cost-effective analysis of sugemalimab plus chemotherapy as first-line treatment for advanced gastric or gastroesophageal junction adenocarcinoma with PD-L1 CPS ≥5. [PDF]

Front Public Health
Zhang Y, He Y, Chen R, You M.
europepmc   +1 more source

Alkyne‐Assisted Stereospecific Skeletal Rearrangement via Nonclassical Carbocations

Chemistry – A European Journal, EarlyView.
We report stereospecific nucleophilic substitution of homopropargylic alcohols enabled by alkyne anchimeric assistance. Alcohol activation triggers formation of a nonclassical cyclopropylidenemethyl cation, allowing efficient chirality transfer to densely substituted tertiary homopropargyl fluorides.
Rajan Kumar Kharwar, Kaushalendra Patel, Noam Orbach, Ilan Marek   +3 more
wiley   +1 more source

The Cost-Effectiveness of Sugemalimab Plus CAPOX in Treating Advanced Gastric Cancer: Analysis from the GEMSTONE-303 Trial. [PDF]

Cancers (Basel)
Chueh CH, Huang WM, Hong MY, Tsai YW, Chiang NJ, Chen HL.   +5 more
europepmc   +1 more source

Gibbs energy minimization thermodynamics for CO2 capture by aqueous amines: Conservation laws, concentration variables, and parameter consistency

The Canadian Journal of Chemical Engineering, EarlyView.
We clarify how Gibbs‐energy‐minimization models for aqueous‐amine CO2 capture fail when conservation constraints and concentration conventions are inconsistent. Exact standard‐state conversions and Reaktoro case studies show that P(CO2)‐loading fits can mask non‐unique parameters and wrong speciation, motivating complete water‐inclusive formulations ...
William R. Smith, William Rutherford, Allan M. M. Leal   +2 more
wiley   +1 more source