Results 191 to 200 of about 3,574 (241)

Single-arm, multicentre phase II trial of sintilimab plus platinum-based doublet chemotherapy followed by adaptive radiotherapy strategy for patients with unresectable stage III non-small-cell lung cancer in China: the ART-LUNG 01 study protocol. [PDF]

BMJ Open
Wu L, Ma S, Zhang X, Song Z, Liu X.
europepmc   +1 more source

Nucleophilic Vinylic Substitution of 2,2‐Diaryl‐Substituted 1‐Chlorovinyl p‐Tolyl Sulfoxides With Alkynyllithiums

European Journal of Organic Chemistry, EarlyView.
A nucleophilic vinylic substitution (SNV) reaction of 1‐chlorovinyl p‐tolyl sulfoxides with alkynyllithiums provides a direct route to conjugated enynes. The transformation proceeds with stereochemical retention. Experimental studies and DFT calculations support a concerted SNVπ mechanism. Nucleophilic vinylic substitution (SNV) reactions of 2,2‐diaryl‐
Tsutomu Kimura, Saya Yamamoto, Chie Takase, Yuka Nishimura, Koto Sekiguchi, Tsuyoshi Satoh   +5 more
wiley   +1 more source

Effect of radiation dose on quantification of the liver iron and fat fractions using dual-energy computed tomography and material decomposition. [PDF]

Quant Imaging Med Surg
Shan H, Zhou J, Dai Q, Xie T, Cheng G.
europepmc   +1 more source

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Effects of Bifidobacterium animalis Subsp. Lactis CP-9 on Gut Microbiota and Immune Functions in Healthy Infants. [PDF]

Microb Biotechnol
Zhang L, Song X, Zhang K, Xu X, Guo X, Li W, Zeng X, Xie Y, Nie L, Zhao L, Dai X, Sun J, Yan J, Liu Y, Zhang F, Sun Z.   +15 more
europepmc   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

Exploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma, Hai‐Peng Wang, Yu‐Meng Jiang, Ke Lai, Ming‐Xian Li, Zhen Zhang, Li‐Na Gong, Jing‐Wei Lai, Kai‐Ming Su, Lu‐Yang Wang, Hui Wang, Shan‐Kai Yin, Hao He, Hai‐Bo Shi   +13 more
wiley   +1 more source

Efficacy and safety of PD-1/PD-L1 inhibitors plus chemotherapy versus chemotherapy alone in stage IIIB-IV squamous non-small cell lung cancer: a systematic review and meta-analysis of phase 3 randomized controlled trials. [PDF]

Transl Cancer Res
Pan C, Zhang R, Niu Y, Zhang W, Cai M.
europepmc   +1 more source

Flexible white thermally activated delayed fluorescence polymer with alkyl spacer and side‐chain encapsulation for efficient solution‐processed white organic light‐emitting diodes

FlexMat, EarlyView.
A “gemstone‐necklace” FASCE strategy synthesizes single‐component white polymers (PTF‐Qx) by alternating rigid TADF units with flexible alkyl chains. The non‐doped rigid device achieves a high EQE of 15.66% with stable white emission (CIE: 0.36, 0.46).
Wenhao Zhang, Hongyu Zhuang, Xinxin Ban, Shilong Feng, Tao Xu, Youqiang Qian, Shun Hu, Aiyun Zhu   +7 more
wiley   +1 more source

Comparison of image quality in carotid dual-energy computed tomography angiography at 55 keV virtual monoenergetic imaging using deep learning and adaptive iterative reconstruction algorithm. [PDF]

J Clin Imaging Sci
Liu X, Wang C, Long J, Wu Y, Liu Z, Yu M, Wang C, Xu W, Zhang H, Sun A, Zhang S, Xu K, Meng Y.   +12 more
europepmc   +1 more source

Viability of Tumor Cells in Bone Dust: Implications for Oncologic Skull Base Surgery

Head &Neck, EarlyView.
ABSTRACT Background Head and neck tumors with skull base involvement may require drilling of tumor infiltrated bone. We hypothesize that bone dust generated during this process contains viable tumor cells that may seed the surgical field. Methods Tumors with gross bone invasion were drilled, and dust was collected for H&E, cell viability analysis, and ...
Kelly Bridgham, Hani Samarah, Emma De Ravin, Hannah Kenny, Eric Mastrolonardo, Annie Moroco, Suhao Han, Oliver Abinader, Ramkrishna Mitra, Alban Linnenbach, Gurston Nyquist, Christopher Farrell, Stacey Gargano, Andrew P. South, Adam Luginbuhl   +14 more
wiley   +1 more source