Results 201 to 210 of about 2,712 (288)

Nucleophilic Vinylic Substitution of 2,2‐Diaryl‐Substituted 1‐Chlorovinyl p‐Tolyl Sulfoxides With Alkynyllithiums

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
A nucleophilic vinylic substitution (SNV) reaction of 1‐chlorovinyl p‐tolyl sulfoxides with alkynyllithiums provides a direct route to conjugated enynes. The transformation proceeds with stereochemical retention. Experimental studies and DFT calculations support a concerted SNVπ mechanism. Nucleophilic vinylic substitution (SNV) reactions of 2,2‐diaryl‐
Tsutomu Kimura   +5 more
wiley   +1 more source

Absence seizures: Update on signaling mechanisms and networks

open access: yesEpilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

Triggered Calcium Lightning Programs Cochlear Development

open access: yesExploration, EarlyView.
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma   +13 more
wiley   +1 more source

Flexible white thermally activated delayed fluorescence polymer with alkyl spacer and side‐chain encapsulation for efficient solution‐processed white organic light‐emitting diodes

open access: yesFlexMat, EarlyView.
A “gemstone‐necklace” FASCE strategy synthesizes single‐component white polymers (PTF‐Qx) by alternating rigid TADF units with flexible alkyl chains. The non‐doped rigid device achieves a high EQE of 15.66% with stable white emission (CIE: 0.36, 0.46).
Wenhao Zhang   +7 more
wiley   +1 more source

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