Results 31 to 40 of about 1,639,010 (213)

Effectiveness and tolerability of fenfluramine in pediatric and adult patients with developmental and epileptic encephalopathies: A multicenter, retrospective, real‐world clinical‐practice study

open access: yesEpilepsia, EarlyView.
Abstract Objective Developmental and epileptic encephalopathies (DEEs) are characterized by drug‐resistant seizures and developmental slowing/regression. We examined the efficacy and tolerability of fenfluramine (FFA) in pediatric and adult patients with Lennox–Gastaut syndrome (LGS), Dravet syndrome (DS), and other DEEs.
Vicente Villanueva   +29 more
wiley   +1 more source

Expression and structural analysis of taste receptor genes in Iberian and Duroc pigs

open access: yesGenetics Selection Evolution
Background Taste receptor genes are expressed in sensory cells located in the tongue and influence food preferences, voluntary feed intake, and other relevant traits.
Cristina Óvilo   +9 more
doaj   +1 more source

Optimum mating designs for exploiting dominance in genomic selection schemes for aquaculture species

open access: yesGenetics Selection Evolution, 2021
Background In commercial fish, dominance effects could be exploited by predicting production abilities of the offspring that would be generated by different mating pairs and choosing those pairs that maximise the average offspring phenotype. Consequently,
Jesús Fernández   +2 more
doaj   +1 more source

Characterizing chapeau de gendarme in pediatric epilepsy through systematic video‐EEG evaluation

open access: yesEpilepsia, EarlyView.
Abstract Objective Chapeau de gendarme (CdG) is a subtle but clinically relevant semiology that has been scarcely studied in children. Previous studies have primarily focused on its localizing value in small, surgical cohorts. This study aimed to systematically characterize frequency and clinical features of CdG across the pediatric age spectrum ...
Hanna Barbara Brinkmann   +5 more
wiley   +1 more source

Ethanol Preference Leads to Alterations in Telomere Length, Mitochondria Copy Number, and Antioxidant Enzyme Activity in Zebrafish Brains

open access: yesFrontiers in Bioscience-Landmark, 2023
Background: The motivations for and effects of ethanol consumption vary considerably among individuals, and as such, a significant proportion of the population is prone to substance abuse and its negative consequences in the physical, social, and ...
Izabela Barbosa Moraes   +7 more
doaj   +1 more source

Exometabolomics Reveals Metabolic Modulation Induced by Chia Oil Supplementation in Adipose Tissue Explants From Obese Mice

open access: yesLipids, EarlyView.
The experimental design and the exometabolomic findings obtained by 1H‐NMR analysis of conditioned media from subcutaneous (SAT) and epididymal adipose tissue (EAT) explants of control and obese mice supplemented with chia oil (1.5% (w/w)). Following 8 weeks of control or high‐fat diet and 5 weeks of chia oil supplementation, SAT and EAT explants were ...
Gilson Costa dos Santos Jr   +5 more
wiley   +1 more source

Estudio comparativo de parámetros composicionales y nutricionales en leche de vaca, cabra y búfala, Antioquia, Colombia

open access: yesRevista Colombiana de Ciencia Animal Recia, 2016
La leche es un líquido secretado por las hembras de todas las especies de mamíferos, la cual es utilizada principalmente para satisfacer las necesidades nutricionales de la cría recién nacida. Es una fuente importante de carbohidratos, lípidos, proteínas,
Ricardo Ocampo G.   +3 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva   +23 more
wiley   +1 more source

Urbanization and food transition in the Brazilian Amazon: From wild to domesticated meat

open access: yesPeople and Nature, EarlyView.
Abstract Urbanization is expected to influence food transitions, resulting in a shift from wild foods to more domesticated foods. Concomitantly, food insecurity and urban demand for natural resources, including wildlife, are expected to increase overall, even when the per capita consumption is expected to decrease.
Willandia A. Chaves   +7 more
wiley   +1 more source

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