Results 121 to 130 of about 770,818 (335)

TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1

open access: yesAdvanced Science, EarlyView.
G9a, and DNA Methyltransferase1 (DNMT1) cooperatively modulates E2F1 on the promoter of tumor suppressor p53‐binding protein 2 (TP53BP2) increased autophagy in preeclampsia. TP53BP2 promotes autophagy in trophoblasts through DNA methylation and H3K9me2‐mediated transcriptional regulation.
Nan Jiang   +12 more
wiley   +1 more source

Colorectal Cancer Cell's Weapon: RNF32 Engages SPP1+ Macrophages to Foster Liver Metastasis, Targeted by Indole‐3‐Acetic Acid

open access: yesAdvanced Science, EarlyView.
Cytoplasmic RNF32 fuels CRC liver metastasis by degrading GSK3β, which stabilizes β‐catenin and activates Wnt/EMT. Moreover, RNF32 rewires the metastatic niche: it depletes CD8+/CD4+ T and NK cells while recruiting SPP1+ macrophages (which boost tumor stemness via CD44), fibroblasts, and immunosuppressive monocytes to aid colonization.
Hongyu Wang   +12 more
wiley   +1 more source

Gender-Based Violence Against Women [PDF]

open access: yesJAMA Health Forum, 2021
Agnes, Binagwaho   +2 more
openaire   +2 more sources

Gender-based violence in higher education institutions in Ecuador: a systematic literature review

open access: yesFrontiers in Education
Gender-based violence in Ecuador’s higher education institutions (HEIs) is a structural and widespread problem, rooted in patriarchal sociocultural norms.
Kenia Laz-Figueroa   +4 more
doaj   +1 more source

Religion and Intimate Partner Violence in Chile: Macro- and Micro-Level Influences [PDF]

open access: yes
The Catholic Church has had a strong influence on the Chilean legal and social landscape in ways that have adversely affected victims of intimate partner violence; e.g., it succeeded until just five years ago in blocking efforts to legalize divorce.
Krauss, Ramona   +2 more
core  

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

open access: yesAdvanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao   +8 more
wiley   +1 more source

Comprehensive development and testing of the ASIST-GBV, a screening tool for responding to gender-based violence among women in humanitarian settings [PDF]

open access: gold, 2016
Andrea L. Wirtz   +6 more
openalex   +1 more source

“We are Forgotten”: Forced Migration, Sexual and Gender-Based Violence, and Coronavirus Disease-2019

open access: hybrid, 2021
Jenny Phillimore   +7 more
openalex   +1 more source

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