Results 181 to 190 of about 295,885 (290)

The Emerging Parkinson's Disease Oxylipin‐Ome

Advanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

The complexity of inequity: rethinking global health through lived experience, power, and structural vulnerability. [PDF]

Int J Equity Health
Abdi YH, Abdullahi YB, Ahmed NI, Abdi MS, Bashir SG, Alasow AA.   +5 more
europepmc   +1 more source

Highly Aligned Bacteria Cellulose Yarn Aggregation for Energy Generation and Strain Sensing

Advanced Science, EarlyView.
Although high‐performance bacterial cellulose fibers have attracted significant interest for wearable electronics, a self‐powered and high‐mechanosensitive design is still scarce for achieving an intelligent integrated system. Here, we demonstrate an innovative bio‐fabrication strategy to develop a core‐sheath yarn that features the ordered network and
Chong Gao, Duo Xu, Hui Sun, Sun Ping, Zongxue Gu, Keshuai Liu, Zhiqiang Zhou, Bin Yu, Jian Fang, Weilin Xu   +9 more
wiley   +1 more source

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

Frameworks encompassing intersectional perspective of artificial intelligence in healthcare. Scoping review. [PDF]

Public Health Pract (Oxf)
Amaya-Santos S, Vargas C, Bermúdez-Tamayo C.   +2 more
europepmc   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

Advanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo, Chunru Xu, Shufan Fu, Qiang Cheng, Juan Li, Linkuo Shang, Gaojie Li, Yang Yang, Ying Wang, Yanqing Gong, Shengwei Xiong, Jian Fan, Changwei Yuan, Mei Zhang, Yifan Zuo, Elena Papaleo, Yue Shi, Yuan Liang, Xuesong Li, Hongzhao Li, Weimin Ci   +20 more
wiley   +1 more source

When care meets resistance: professional nurses' real-world struggles in providing primary health services to LGBTQI communities in Amahlathi, Eastern Cape Province, South Africa. [PDF]

Front Med (Lausanne)
Dube M, Manamela LE, Sumbane GO, Mokhwelepa LW.   +3 more
europepmc   +1 more source

Species Dependent Toxicity Comparison Outcome

Advanced Science, EarlyView.
By quantitatively assessing and comparing toxicity responses across different animal species and material compositions, our data reveal that toxicity rankings among different materials may be reversed across species. ABSTRACT Toxicity comparison plays a crucial role in material selection across diverse application fields.
Lian Xiao, Zhan Yu, Sihang Liu, Yuheng Liu, Chong Deng, Yugang Zhao, Yi Huang, Zhi‐Gang Zheng   +7 more
wiley   +1 more source

Dismantling the Diagnostic Construct of Borderline Personality Disorder: A Critical Discourse Analysis. [PDF]

Int J Ment Health Nurs
Cobbaert L, Maloney E, Harding K, James S.   +3 more
europepmc   +1 more source

Gender-sensitive integrated farming system: A framework for promoting enhanced women participation and food security

International Journal of Agriculture Extension and Social Development
Ankita Sahu, Arun Kumar Panda, Praveen Jakhar, Mridula Devi   +3 more
openaire   +1 more source