Results 291 to 300 of about 6,703,893 (341)

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

A qualitative study on healthcare providers' biases towards transgender and gender diverse people accessing contraceptive care. [PDF]

Sex Reprod Health Matters
Zia Y, Folse C, Lawyer A, Zeid F, Alvarez A, Somerson E, Davis KA, Menkin D, Hawkins M, Hastings J, Harper C.   +10 more
europepmc   +1 more source

Sex and gender [PDF]

, 2010
Hyde, Martin, Piercy, Hilary, Salway, Sarah   +2 more
core  

The Tumor‐to‐Endothelial Transfer of FTO Promotes Vascular Remodeling and Metastasis in Nasopharyngeal Carcinoma

Advanced Science, EarlyView.
Integrated omics analysis of matched primary and liver metastatic NPC tumors reveals a unique NOTCH1+ CSC subpopulation exhibiting enhanced stemness properties and tumorigenic capacity. With in vitro and in vivo assays, exosomal transfer of tumor‐derived FTO from NOTCH1+ cells to the endothelium promotes vascular permeability and metastatic potential ...
Chun Wu, Xuefei Liu, Liwen Gu, Jingru Lian, Yuting Wang, Yixin Cheng, Lianhui Duan, Guanyin Huang, Siqi Chen, Boxi Zhao, Sailan Liu, Yufan Yang, Shuqian Zheng, Zijian Lu, Wanping Guo, Jianyang Hu, Wenjing Wang, Zhixiang Zuo, Haiqiang Mai, LinQuan Tang, Songfa Zhang, Feiqiu Wen, Xin Hong, Ling Guo   +23 more
wiley   +1 more source

Progress and stagnation: A comparative study of gender representation in Chinese language textbooks for junior high school between 2001 edition and 2023 edition. [PDF]

PLoS One
Yang X, Sun Y, He H.
europepmc   +1 more source

Gender Roles and Inequalities in the Nigerian Labour Market

, 2019
Sue Enfield
openalex   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

Mental Health and Care Denial in Transgender Youth. [PDF]

JAMA Psychiatry
Eckstrand KL, Fonseca EF, Baker K, Dalke K.   +3 more
europepmc   +1 more source

Reinforcing intensive motherhood: A study of gender bias in parental responsibilities allocation by large language models. [PDF]

PLoS One
Xiu J, Sun Y.
europepmc   +1 more source

Disordered eating in autistic trans and gender diverse people: a lived experience-led scoping review. [PDF]

J Eat Disord
White LCJ, Schweizer K, Thomas KS.
europepmc   +1 more source