Results 291 to 300 of about 6,987,836 (365)

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

open access: yesAdvanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng   +13 more
wiley   +1 more source

The Emerging Parkinson's Disease Oxylipin‐Ome

open access: yesAdvanced Science, EarlyView.
ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley   +1 more source

Gender gaps in reading increase during unplanned and planned school closures. [PDF]

open access: yesProc Natl Acad Sci U S A
Smith E   +3 more
europepmc   +1 more source

Facial expression processing is modulated by face gender and anxiety levels in developing youth. [PDF]

open access: yesDev Cogn Neurosci
Bai H   +13 more
europepmc   +1 more source

Socio-Emotional Skills and Physical Activity in Primary and Secondary Education Students. [PDF]

open access: yesJ Sch Health
Morcillo-Martínez A   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy