Results 41 to 50 of about 2,430,800 (297)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Social Sciences, 2022 The COVID-19 pandemic has brought into stark focus the economic inequities faced by precarious, criminalized and racialized workers. Sex workers have been historically excluded from structural supports due to criminalization and occupational stigma ...
Jennie Pearson +6 more
doaj +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Child and Adolescent Psychiatry and Mental Health, 2023 Background Gender-diverse young people experience a cisnormative world and are subject to unique minority stressors, which have been found to contribute to adverse mental health.
Daisy Haywood +3 more
doaj +1 more source
Gender Inequality in Paid and Unpaid Work During Covid‐19 Times [PDF]
, 2021 Lídia Farré +3 more
openalex +1 more source
YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma
Molecular Oncology, EarlyView.The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy +9 more
wiley +1 more source
Mimetic Machines in the Uncanny Valley
Identities, 2021 Uncanny valley (不 気 味 の 谷 ) is a notion introduced by the Japanese robotics professor Masahiro Mori in 1970. The basic claim of his hypothesis states that the anthropomorphic machines cause uncanny effect due to their imperfect resemblance to the human ...
Identities Journal for Politics, Gender and Culture +1 more
doaj
Gender and entrepreneurship: Research frameworks, barriers and opportunities for women entrepreneurship worldwide [PDF]
, 2021 Joyce A. Strawser +2 more
openalex +1 more source
, 2018 The fraction of women in economics has grown significantly over the last forty years. In spite of this, the differences in research output between men and women are large and persistent. These output differences are related to differences in the co-authorship networks of men and women: women have fewer collaborators, collaborate more often with the ...
Ductor, L, Goyal, S., Prummer, A.
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source