Results 241 to 250 of about 4,702,096 (304)

A comprehensive semantics for agreement [PDF]

, 2009
Sauerland, Uli
core  

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

The German translation of the Oxford utilitarianism scale: Validation and the impact of the Covid-19 pandemic on the observations. [PDF]

PLoS One
Ambrasė A, Hendrickx M, Grahlow M, Wong HY, Derntl B.   +4 more
europepmc   +1 more source

Behavior‐ and Cell Type‐Specific Cortico‐Striatal Decoupling in a Parkinson's Disease‐Like Mouse Model

Advanced Science, EarlyView.
Utilizing dual‐site fiber photometry, this study examines cortico‐striatal coupling with cell type resolution, identifying behavior‐ and cell type‐specific cortico striatal decoupling and its dopamine‐dependent mechanism in a Parkinson's disease mouse model.
Xu‐Ran Yao, Yang Liu, Wei‐Tong Zheng, Mao‐Qing Huang, Kai‐Wen He   +4 more
wiley   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Agree to Disagree? Fertility Intentions Among Mixed Couples in Sweden. [PDF]

Eur J Popul
Mussino E, Uggla C.
europepmc   +1 more source

Preparing the next generation of Complex Networks and Systems scientists: Evaluation results for the Complex Networks and Systems NSF research training program at Indiana University. [PDF]

PLoS One
Ginda M, Börner K, Scrivner O, Trochim W, Rocha LM, Šabanović S.   +5 more
europepmc   +1 more source

Waverly Central School District and Waverly Food Service Employees Association (2005) [PDF]

, 2005

core   +1 more source

Prevalence of Sexual and Gender Minorities in a Swedish Adolescent Community Population: Stability vs. Fluidity of Sexual Orientation. [PDF]

Arch Sex Behav
Claesdotter-Knutsson E, Kapetanovic S, Skoog T, Askelöf S, Håkansson A, Gerdner A.   +5 more
europepmc   +1 more source

Editorial: Exploring female intuition: insights into gendered information processing. [PDF]

Front Sociol
Isenman L, Sinclair M.
europepmc   +1 more source