Results 71 to 80 of about 412,323 (297)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Biden Administration Revises Federal Government Position on Validity of the Equal Rights Amendment [PDF]

open access: yes, 2022
Today the Department of Justice (DOJ) Office of Legal Counsel (OLC) released a new opinion on the ratification of the Equal Rights Amendment (ERA). This opinion revises a 2020 OLC opinion issued under the Trump administration that declared the ERA a dead
Center for Gender and Sexuality Law,
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Understanding the association between unmet dental care needs and household food security status among older people in Ghana

open access: yesBMC Oral Health, 2023
The literature recognizes food insecurity as a barrier to access to health care services. However, we know very little about the association between food insecurity and unmet dental care needs among older people in Ghana.
Daniel Amoak   +7 more
doaj   +1 more source

The ERA Brief June 2021 [PDF]

open access: yes, 2021
At the ERA Project we get asked all the time: “Why do we need the Equal Rights Amendment (ERA)?” “Doesn’t the Constitution already prohibit sex discrimination?” “What difference would it make to add explicit sex discrimination protections in the ...
Center for Gender and Sexuality Law,
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

The Equal Rights Amendment and LGBTQ Rights, Including Marriage Equality [PDF]

open access: yes, 2022
Below, we provide an analysis of the potential for the Equal Rights Amendment (ERA) to strengthen protections for LGBTQ rights, including marriage equality. Currently pending before the U.S.
Center for Gender and Sexuality Law,
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Institutional Ethnography Research in Global South Settings

open access: yesInternational Journal of Qualitative Methods, 2016
Within institutional ethnography (IE), texts—reproducible written and graphic materials—are understood to play a central role in coordinating social relationships.
Sarah Rudrum
doaj   +1 more source

Queer Farmers: Sexuality and the Transition to Sustainable Agriculture [PDF]

open access: yes, 2016
Intimate relationships are foundational to farm viability. Such relationships affect how farmers share tasks, earn income, and access land, yet the role of sexuality and heteronormativity in agriculture remains understudied.
Leslie, Isaac
core   +2 more sources

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