Results 161 to 170 of about 2,502,899 (408)

Genetic Regulation of Alternative Polyadenylation Provides Novel Insights into Molecular Mechanisms Underlying Non‐small Cell Lung Cancer

Advanced Science, EarlyView.
Compared with the non‐risk G allele of rs9606, the risk T allele of rs9606 decreases the binding affinity of NUDT21 for LYRM4, triggering 3'UTR shortening that stabilizes LYRM4 mRNA and elevates its expression. Increased LYRM4 expression promoted malignant phenotypes of non‐small cell lung cancer (NSCLC) cells through modulating ferroptosis, supporting
Meng Jin, Yongbiao Huang, Bin Li, Yuan Wang, Yan Li, Zhirui Chen, Zhe Tang, Chaofan Liu, Lei Zhang, Xianglin Yuan, Jianbo Tian, Bo Liu   +11 more
wiley   +1 more source

Gender, Social Capital and Collective Action: A gender perspective on collective sustainability of water resource governance in west Nepal [PDF]

, 2019
In Nepal, as in other South Asian countries, water resource development is often considered to be a primarily technological challenge, requiring engineered solutions.
Clement, Floriane, Shrestha, Gitta
core  

Promoting Gender Equality

, 2018
In the following the Nordic legal feminism is discussed. Nordic gender equality policy and law have been integrated with the welfare state, promoting general equality. All Nordic countries have ascribed to strategic equality policies, however, with somewhat different vigour.
openaire   +2 more sources

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

Pathways between childhood trauma, intimate partner violence, and harsh parenting: findings from the UN Multi-country Study on Men and Violence in Asia and the Pacific

The Lancet Global Health, 2017
Summary: Background: Although childhood trauma and violence against women are global public health issues, few population-based data from low-income and middle-income countries exist about the links between them.
Emma Fulu, DrPhD, Stephanie Miedema, MA, Tim Roselli, BSc, Sarah McCook, MA, Ko Ling Chan, PhD, Regine Haardörfer, PhD, Rachel Jewkes, ProfMBBS MD, Emma Fulu, Rachel Jewkes, Xian Warner, Stephanie Miedema, Tim Roselli, James Lang, Ruchira Tabassum Naved, Hamidul Huque, Subrina Farah, Muhammad Mizanur Rashid Shuvra, Arthur Erken, Wang Xiangxian, Fang Gang, Li Hongtao, Zeljka Mudrovcic, Wen Hua, Arie Hoekman, Elina Nikulainen, Bernard Coquelin, Mariam Khan, Wenny Kusuma, Clara Magariño Manero, Freya Larsen, Emma Fulu, Xian Warner, Saba Moussavi, Neloufer de Mel, Pradeep Peiris, Shyamala Gomez, Social Indicator Team, Kamani Jinadasa, Rachel Jewkes, Yandisa Sikweyiya, Nwabisa Shai, Francesca Drapuluvik-Tinabar, Peterson Magoola, Anthony Agyenta, Thomas Shanahan, Tracy Vienings, Rachel Jewkes, Claudia Garcia-Moreno, Ruchira Tabassum Naved, Kamani Jinadasa, Tracy Vienings, Wenny Kusuma, Rachel Jewkes, Raewyn Connell, Gary Barker, Alan Greig, Rahul Roy, Ravi Verma, Kalyani Menon Sen, Scott Johnson   +59 more
doaj  

Gender Equality in Educational Achievement: An East-West Comparison [PDF]

, 2004
Sylke V. Schnepf
openalex   +1 more source

Gender Equality in Virtual Work I.: Risks [PDF]

, 2018
This article focuses on gender equality in virtual work, taking special account of the regulatory challenges. It contributes to broader debates on the workers' situation in the sharing economy in two ways.
Kovacs, Erika
core  

An Explainable Multimodal Artificial Intelligence Model Integrating Histopathological Microenvironment and EHR Phenotypes for Germline Genetic Testing in Breast Cancer

Advanced Science, EarlyView.
This study presents an explainable multimodal AI model, MAIGGT (Multimodal Artificial Intelligence Germline Genetic Testing), that combines whole‐slide histopathology with clinical data for accurate germline BRCA1/2 mutation prescreening. By integrating digital pathology and EHR phenotypes, MAIGCT enables cost‐effective, scalable hereditary breast ...
Zijian Yang, Changyuan Guo, Jiayi Li, Yalun Li, Lei Zhong, Pengming Pu, Tongxuan Shang, Lin Cong, Yongxin Zhou, Guangdong Qiao, Ziqi Jia, Hengyi Xu, Heng Cao, Yansong Huang, Tianyi Liu, Jian Liang, Jiang Wu, Dongxu Ma, Yuchen Liu, Ruijie Zhou, Xiang Wang, Jianming Ying, Meng Zhou, Jiaqi Liu   +23 more
wiley   +1 more source

Gender Equality from a Constitutional Perspective: The Case of Turkey [PDF]

, 2004
Hilal Elver
openalex   +1 more source

LIMK1 as a Novel Kinase of β‐Catenin Promotes Esophageal Cancer Metastasis by Cooperating With CDK5

Advanced Science, EarlyView.
Li et al. innovatively map the kinase‐substrate network in esophageal cancer metastasis. Their study demonstrates that LIM domain kinase 1 (LIMK1) and Cyclin‐dependent kinase 5 (CDK5) synergistically increase the phosphorylation of β‐catenin, thereby activating the Wnt/β‐catenin signaling pathway to promote esophageal cancer metastasis.
Shu‐Jun Li, Zhuo‐Ran Liang, Zhi‐Chao Liu, Xue‐Ping Luo, Jun‐Yi Li, Xiao‐Mei Yu, Xuan‐Zhang Huang, Yan He, Tao‐Yang Xu, Jiao‐Jiao Xu, Shao‐Cong Peng, Yu‐Xiang Song, Yan He, Xiao‐Wan Zhuang, Can‐Can Zheng, Fan Zhang, Alfred King‐Yin Lam, Wei Dai, Ming‐Liang He, Bo Liu, Qi Zhao, Guo‐Liang Lu, Jin‐Bao Liu, Zhen‐Ning Wang, Zhi‐Gang Li, Ze‐Xian Liu, Wen‐Wen Xu, Bin Li   +27 more
wiley   +1 more source