Results 221 to 230 of about 2,619,234 (375)

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

Advanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani, Eric Reed, Kevin B Chandler, Prisma Lopez, Hannah Lords, Harold Bae, Catherine E Costello, Matthew Au, Lingyi Lynn Deng, Mengze Li, Qingyan Xiang, Heeju Noh, Lance Pflieger, Cory Funk, Noa Rappaport, Marianne Nygaard, Meghan I Short, Michael Brent, Stefano Monti, Stacy L Andersen, Thomas T Perls   +20 more
wiley   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Feminization of the precarious at the UNAM: Examining obstacles to gender equality. [PDF]

PLoS One
Ciccia L, Espinosa-Lugo G, Garcia-Guzman G, Gasca-Pineda J, Velez P, Espinosa-Asuar L.   +5 more
europepmc   +1 more source

FXYD3 Promotes Tumor Progression by Binding With IRF7 to Regulate JAK2/STAT5 Signaling in Intrahepatic Cholangiocarcinoma

Advanced Science, EarlyView.
FXYD3 binds IRF7 via its 60–87aa domain, triggering a cGAS/STING‐mediated positive feedback loop amplified by type I interferon. This sustains JAK2/STAT5 activation, accelerating ICC progression. Targeting FXYD3 with siFXYD3@PEP suppresses tumors and enhances chemotherapy sensitivity. Abstract Intrahepatic cholangiocarcinoma (ICC) has a poor prognosis,
Yan Zhou, Xiaofeng Shen, Shuo Zhang, XiaoHong Pu, Zipeng Xu, Xiang Zhao, Wei Feng, Yuan Liang, Xingtao He, Aihua Yang, Yudong Qiu, Yihang Yuan, Chaobo Chen, Jun Chen   +13 more
wiley   +1 more source

Gender Equality Stock-Take into the WHO Regional Office for Africa's Transformation Agenda: Progress and Opportunities. [PDF]

J Healthc Leadersh
Chingarande SD, Rwamatwara E, Kithinji D, Nsarhaza K.   +3 more
europepmc   +1 more source

Financial independence and gender equality

Ana Stegarescu, Andrei Petroia
openalex   +2 more sources

HOW CAN HIGHER EDUCATION PROMOTE GENDER EQUALITY, DIVERSITY AND NON-DISCRIMINATION?

, 2022
Merja Drake, Päivi-Katriina Juutilainen, Liisa Vanhanen-Nuutinen, Pirjo Aura   +3 more
openalex   +2 more sources

The silent voices: Pupil participation for gender equality and diversity [PDF]

, 2020
Britt‐Inger Keisu, Björn Ahlström
openalex   +1 more source

"Gender Inequality in a Globalizing World" [PDF]

Emphasis on market-friendly macroeconomic and development strategies in recent years has resulted in deleterious effects on growth and well-being, and has done little to promote greater gender equality.
Stephanie Seguino
core  

The Gender-Equality Paradox in Science, Technology, Engineering, and Mathematics Education

Psychology Science, 2018
G. Stoet, D. Geary
semanticscholar   +1 more source