Results 231 to 240 of about 2,539,672 (291)

Suicidal Behaviour, Self-Harm and Related Factors: A Retrospective Study from the Adolescent Psychiatric Unit. [PDF]

Children (Basel)
Lesinskienė S, Zabarauskaitė M, Valiulis T, Dailidė G, Germanavičius A.   +4 more
europepmc   +1 more source

Reproductive History and Retirement: Gender Differences and Variations Across Welfare States [PDF]

Hank, Karsten, Korbmacher, Julie
core  

Neuronal Cholesterol Deficiency Mediated by Astrocytic SREBP2 Downregulation Leads to Postoperative Cognitive Dysfunction Through Impairment of Hippocampal Synaptic Plasticity and Excitatory Synaptic Transmission

Advanced Science, EarlyView.
The results showed that the reduction of plasma 24‐hydroxycholesterol (24‐OHC) was related to the cognitive decline in elderly surgical patients. Neuroinflammation induced by anesthesia and surgery significantly downregulated SREBP2 in hippocampal reactive astrocytes, resulting in reduced cholesterol synthesis.
He Huang, Chenrui Zhou, Chen Chen, Huimei Tang, Wei Dong, Jie Wan, Weiye Kang, Ao Sun, Yiqi Liu, Chunhui Jin, Xiaobin Lyu, Yankun Zhu, Chenghua Zhou, Yuqing Wu   +13 more
wiley   +1 more source

Discrimination, stalking, sexual harassment and sexual violence at the university - exploring and predicting pattern-based subcategories among students and staff in a German university sample. [PDF]

BMC Public Health
Kaufmann MT, Preisendanz N, Fegert JM, Clemens V.   +3 more
europepmc   +1 more source

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

Advanced Science, EarlyView.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu, Xiaoyu Yao, Qingyang Wang, Mengrui Yang, Runze Li, Jiangjiang Qin, Jing Zhuang, Changgang Sun   +7 more
wiley   +1 more source

Longitudinal body mass index exposure-based threshold to prevent mortality for populations with type 2 diabetes mellitus. [PDF]

Cell Rep Med
Hu T, Cai R, Xu Y, Wang C, Shen Y, Wu L, Chen L, Xia T, Bao Y.   +8 more
europepmc   +1 more source

Neurocognitive risk markers in first-episode major depressive disorder with positive family history: a large-scale case-control study. [PDF]

Front Psychiatry
Li Z, Pan M, Zhang X, Wang A, Fang W, Guan J, Zhang B, Cheng X.   +7 more
europepmc   +1 more source

Fear of falling among housebound older adults: a quantitative study. [PDF]

BMC Geriatr
Yang K, Bai J, Zhen F, Xing F, YounG FC, WanG Y.   +5 more
europepmc   +1 more source