Results 91 to 100 of about 1,446,772 (324)

NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao, Shikuan Din, Zhengkang Fu, Qian Sun, Xiwei Zhu, Yuxin Wei, Huan Qu, Xinyi Zhang, Jiaxuan Liu, Chuhua Fu, Qianxue Chen   +10 more
wiley   +1 more source

Is bioimpedance analysis feasible in transgender men?

Clinical Nutrition Open Science
Summary: Background & aims: Accurate fat mass (FM) and muscle mass (MM) assessment is an informative marker of an individual's health. However, the optimal method for assessing body composition in transgender men remains to be determined.
Signe Graungaard, Liva Bundgaard Larsen, Peter Vestergaard, Niels Henrik Bruun, Astrid Ditte Højgaard, Jakob Dal   +5 more
doaj   +1 more source

Moving beyond sex: Assessing the impact of gender identity on human papillomavirus vaccine recommendations and uptake among a national sample of rural-residing LGBT young adults

Papillomavirus Research, 2017
Background: While national human papillomavirus (HPV) vaccination estimates exist by sex, little is known about HPV vaccination rates by gender identity. Methods: We conducted a self-administered, anonymous online cross-sectional survey, with recruitment
Robert A. Bednarczyk, Jennifer L. Whitehead, Rob Stephenson   +2 more
doaj   +1 more source

''Sex Changes'? Paradigm Shifts in 'Sex' and 'Gender' Following the Gender Recognition Act?' [PDF]

Gender transformations are normatively understood as somatic, based on surgical reassignment, where the sexed body is aligned with the gender identity of the individual through genital surgery – hence the common lexicon \'sex change surgery\'. We suggest
Lewis Turner, Stephen Whittle
core  

Gender-Inclusive Library Workgroup Report [PDF]

, 2018
The Gender-Inclusive Workgroup explored how VCU Libraries can better serve trans and gender-nonconforming users and staff. The group’s recommendations cover library spaces, staff, systems, services, and culture.
Barkley, Steve, Coghill, Donna E., Doherty, M. Teresa, Palmer, Liam, White, Erin   +4 more
core   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Transphobia in the United Kingdom: a public health crisis

International Journal for Equity in Health
Background The moral panic surrounding trans, non-binary, and gender diverse (TGD) lives in the United Kingdom (UK) has been incited by high-level political and government actors and exacerbated by pervasive misinformation in social and press media. This
Dean J. Connolly, Catherine Meads, Alanna Wurm, Chay Brown, Jacob Bayliss, T. C. Oakes-Monger, Alison M. Berner   +6 more
doaj   +1 more source

From Gender Identity Oppression to Power Reversal in the Novel Calabai [PDF]

, 2018
Recently, the sociocultural problems of transgender have shown an increase. The novel, Calabai, vividly depicts various acts of violence perpetrated by Bugis tribesmen against transgender members of the community.
Triadnyani, I. G. (I)
core  

Prediction Model for Etiologic Differentiation of Isolated Vestibular Syndrome in Emergency Settings

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to develop and validate a predictive model for differentiating central from peripheral etiologies in patients with isolated vestibular syndrome (VS). Methods In this multicenter retrospective cohort study, 506 patients with isolated VS from five hospitals were divided into derivation (n = 301) and validation (n = 205)
Guo Wenting, Du Liping, Yang Yi, Hu Jin, Ye Bijun, Wang Jianer, Liu Shuangsi, Guo Shunyuan, Cai Xiaofeng, Wang Huiyuan, Wu Bin, Yu Xiang, Shi Tianming   +12 more
wiley   +1 more source

Clinical Characteristics and Outcomes of Early‐Onset Versus Late‐Onset LGI1‐Antibody Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Leucine‐rich glioma‐inactivated 1 antibody (LGI1‐Ab) encephalitis predominantly affected older individuals, but has also been reported in younger patients. However, the demographic, clinical, and prognostic characteristics of early‐onset LGI1‐Ab encephalitis have yet to be systematically elucidated. This study aims to systematically
Yu Kong, Shasha Yu, Jing Zhang, Yu Zu, Yujing Zhang, Jing Lv, Xuyang Cao, Xuedan Feng   +7 more
wiley   +1 more source