Results 191 to 200 of about 215,175 (260)

eEF1G Orchestrates Translation to Ensure Meiotic Progression in Transcriptionally Quiescent Spermatocytes

open access: yesAdvanced Science, EarlyView.
eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu   +12 more
wiley   +1 more source

Single‐Cell and Spatial Transcriptomics Unveil Key Regulators Governing Cell Differentiation for Schistosoma japonicum Sexual Development

open access: yesAdvanced Science, EarlyView.
Using single‐cell and spatial transcriptomics, we identified key regulators that govern cell differentiation involved in parasite development and egg laying in Schistosoma japonicum. This comprehensive study establishes a foundational resource for understanding schistosome biology, deciphers the regulatory programs underlying cell differentiation and ...
Zhigang Lu   +9 more
wiley   +1 more source

Calcineurin‐Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata

open access: yesAdvanced Science, EarlyView.
Caspofungin heteroresistance is prevalent in clinical Candida glabrata isolates and depends on calcineurin‐mediated stress adaptation. This transient phenotype serves as a reservoir for resistance evolution, enabling the emergence of stable resistant descendants under prolonged drug pressure.
Yanyu Su   +7 more
wiley   +1 more source

Replication of the Police and Law Enforcement (PLE) Scale and extension to intersectional race/ethnicity and gender identity groupings. [PDF]

open access: yesCultur Divers Ethnic Minor Psychol
Lopez-Vergara HI   +4 more
europepmc   +1 more source

Incident Atherosclerotic Cardiovascular Disease Among Veterans by Gender Identity: A Cohort Study. [PDF]

open access: yesJ Gen Intern Med
Streed CG   +10 more
europepmc   +1 more source

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