Results 291 to 300 of about 1,417,496 (337)

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

open access: yesAdvanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani   +20 more
wiley   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

open access: yesAdvanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou   +9 more
wiley   +1 more source

Navigating sexual orientation and gender identity data privacy concerns in United States genetics practices. [PDF]

open access: yesJ Genet Couns
Zayhowski K   +7 more
europepmc   +1 more source

Adolescent Comfort With Sexual Orientation and Gender Identity Collection and Preferences for Electronic Health Record Documentation in the Ambulatory Setting. [PDF]

open access: yesJ Adolesc Health
Pourian J   +8 more
europepmc   +1 more source

Sex, Sexual Orientation, and Gender Identity Measurement in Health Research: A Systematic Review and Narrative Synthesis. [PDF]

open access: yesLGBT Health
Rich AJ   +7 more
europepmc   +1 more source

Gender identity and mental health inequalities 2001-2022: population-level evidence from an Australian cohort study. [PDF]

open access: yesBMJ Ment Health
Saxby K   +6 more
europepmc   +1 more source

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