Results 51 to 60 of about 215,175 (260)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Effect of gender-affirming treatments on depression and anxiety symptoms in transgender people: a retrospective cohort study

open access: yesFrontiers in Psychiatry
IntroductionGiven the unique mental health challenges among transgender individuals, it is imperative to understand the effectiveness of gender-affirming treatments in alleviating psychological distress. The existing literature gap calls for studies with
Chun Yip Wong   +5 more
doaj   +1 more source

VOICES OF WOMEN FROM THE FAVELAS

open access: yesSur: International Journal on Human Rights, 2021
This essay intends to make readers listen to the voices of women from the Maré favela complex located in Rio de Janeiro. We cross-referenced data from “Mapa social do corona”, a bulletin produced by Observatório de Favelas with reports on the everyday ...
Angélica Ferrarez
doaj  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

GENDER AND LANGUAGE: EXAMINING THE USE OF DIAGNOSTIC LANGUAGE IN THE DISCUSSION OF GENDER VARIANCE

open access: yesInternational Journal of Child, Youth & Family Studies, 2014
Gender is considered to be one of the major organizing principles in an individual’s life; however, a unified understanding of what gender is and how gender identity is developed continues to spark debate and discussion for practitioners and academics ...
M. Walker
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Educational intervention on sexual violence to empower university students in developing healthy affective-sexual relationships

open access: yesHeliyon
Introduction: Sexual violence (SV) is frequent in universities, and a link has been demonstrated between SV and toxic substance use by university students in leisure settings. In Spain there is little scientific evidence in this regard, and SV prevention
Alba Berenguer-Simon   +5 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen   +7 more
wiley   +1 more source

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