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Targeting DAP5 Disrupts Alternate Mode of Translational Initiation in Tregs and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
Regulatory T cells (Tregs) suppress antitumor immunity. This study identifies that the translation scaffold DAP5/eIF4G2 is upregulated in tumor‐infiltrating Tregs (ti‐Tregs). DAP5 mediates an alternate translation mode to sustain CD25 and MCL‐1 expression, which is critical for ti‐Treg stability and survival in the tumor microenvironment.
Xiaojiang Lai, Guihong Pan, Xixi Feng, Jun Zhang, Yunxia Li, Shanmeizi Zhao, Zhenming Lin, Yun Feng, Wei Bao, Hongyan Yang, Chengmei Xie, Chen Huang, Jun Wang   +12 more
wiley   +1 more source

Exploring the perceived impact and influence of women leaders across sub-Saharan Africa on health policy and gender equity. [PDF]

BMJ Glob Health
Kalbarczyk A, Nakatabira M, Banchoff K, Ahmed I, Abdulkader S, Argefa TG, Jacobs C, Kuo H, Rabary M, Morgan R.   +9 more
europepmc   +1 more source

Patient Satisfaction and Its Determinants in Outpatient Clinics of Ministry of Health Maternal and Child Hospitals in Saudi Arabia: A Survey Analysis. [PDF]

Inquiry
El Dalatony MM, Aldawsari MA, Alghamdi KM, Alabdullatif LM, Fussi NM, Alothman NA, Alalweet RM, Alrahily SS, Aldossary MS.   +8 more
europepmc   +1 more source

Gender-specific motivation for training in sexual history. [PDF]

Front Med (Lausanne)
Platzer N, Utz J, Bailer M, Triebner N, Kersten GM, Kornhuber J, Spitzer P.   +6 more
europepmc   +1 more source

'I fit the category of the box, it just doesn't describe me well.' Exploring the perspectives of autistic women and gender-diverse individuals on self-report autism measures. [PDF]

PLoS One
Uglik-Marucha N, Show S, Vitoratou S, Happé F, Belcher H.   +4 more
europepmc   +1 more source

Editorial: Pride in Frontiers in Human Neuroscience. [PDF]

Front Hum Neurosci
Manca R, Albrechet-Souza L, Moreno JA.
europepmc   +1 more source

Women rights from Islamic perspectives: navigating rights, challenges and contemporary perspectives. [PDF]

Front Sociol
Saifullin D, Okan S, Akimkhanov A.
europepmc   +1 more source

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Gender issues

Neurologic Clinics, 2005
Elizabeth Plaster, Pam Schiller
  +9 more sources