Results 191 to 200 of about 1,573,573 (279)

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Gender roles in ruminant disease management in Uganda: Implications for the control of peste des petits ruminants and Rift Valley fever. [PDF]

PLoS One
Namatovu J, Lule P, Asindu M, Campbell ZA, Tumusiime D, Kiara H, Bett B, Roesel K, Ouma E.   +8 more
europepmc   +1 more source

Cyber dating abuse and ghosting behaviours: personality and gender roles in romantic relationships. [PDF]

Curr Issues Personal Psychol, 2022
Biolcati R, Pupi V, Mancini G.
europepmc   +1 more source

Ribosome Homeostasis Regulated by SETD2 Preserves Intestinal Epithelial Barrier

Advanced Science, EarlyView.
SETD2 ablation causes dysregulation and recruitment defects of ribosome biogenesis factors, resulting in translational disorders of barrier maintenance genes, thereby compromising the intestinal barrier. These findings unveil a previously unappreciated role of ribosome biogenesis and translational regulation in preserving the intestinal epithelial ...
Hanyu Rao, Aiting Wang, Yue Xu, Wenxin Feng, Chunxiao Ma, Ziyi Wang, Wei Zhang, Wenqiong Su, Xiuying Xiao, Wei‐Qiang Gao, Xianting Ding, Li Li   +11 more
wiley   +1 more source

Sexual and reproductive health in Pakistan: a qualitative exploratory study of gender roles, family planning and adolescent health in Chitral, Gilgit-Baltistan and Sindh. [PDF]

BMJ Public Health
Ali TS, Asif N, Adnan F, Farooq M, Shahid S, Bhutto K, Lashari L, Sarfaraz A, Khan MB, Memon ZA, Soofi S, Bhutta ZA.   +11 more
europepmc   +1 more source

Gender roles, generational changes and environmental challenges: an intersectional interpretation of perceptions on healthy diets among iTaukei women and men in Fiji. [PDF]

Public Health Nutr, 2022
McKenzie BL, Waqa G, Hart AC, Moala Silatolu A, Palagyi A, Norton R, McLean R, Webster J.   +7 more
europepmc   +1 more source

Remimazolam Ameliorates Autistic‐Like Behaviors via Suppression of Ferroptosis in VTA Dopaminergic Neurons in a Mouse Model of ASD

Advanced Science, EarlyView.
The ultra‐short‐acting sedative remimazolam has a sustained therapeutic effect on the core symptoms of VPA‐exposed mice. Remimazolam, a GABA agonist, exerts its therapeutic effects by protecting dopamine neurons in the VTA of VPA‐exposed mice. Meanwhile, ferroptosis is the critical mechanism by which remimazolam protects VTA dopaminergic neurons and ...
Yuxin Zhang, Jianwei Lin, Chaoyang Tong, Xin Fu, Mengqin Shan, Yue Huang, Kan Zhang, Jijian Zheng   +7 more
wiley   +1 more source

Sex as Boys' Fame, But Girls' Shame: Adversarial Adolescent Gender Roles and Gender-based Violence in Guyana. [PDF]

J Interpers Violence, 2022
Rodney R, Gastaldo D, Trotz DA, Crooks CV.   +3 more
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Rape Myths, Gender Roles, and Perceptions of Sexuality: Differences Among Ultra-Orthodox, Formerly Ultra-Orthodox, and Secular Jewish Women. [PDF]

Int J Offender Ther Comp Criminol
Shechory Bitton M, Ben Admon T.
europepmc   +1 more source