Results 271 to 280 of about 46,113,995 (405)

RPL6 Interacts with HMGCS1 to Stabilize HIF‐1α by Promoting Cholesterol Production in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
The study found that RPL6 is frequently upregulated in HCC tissues with extrahepatic metastasis. Elevated RPL6 bound to and increased the stability of HMGCS1 mRNA, thereby enhancing intracellular cholesterol levels. Subsequently, increased cholesterol promotes cancer metastasis in HCC by stabilizing HIF‐1α protein.
Minli Yang   +15 more
wiley   +1 more source

Decolonize Gender Studies!

open access: yes, 2018
dos Santos Pinto, Jovita   +1 more
openaire   +2 more sources

Ligilactobacillus Murinus and Lactobacillus Johnsonii Suppress Macrophage Pyroptosis in Atherosclerosis through Butyrate‐GPR109A‐GSDMD Axis

open access: yesAdvanced Science, EarlyView.
Oral aspirin administration induces intestinal expansion of Lactobacillus murinus and Lactobacillus johnsonii, which suppresses the progression of atherosclerosis. This microbial expansion significantly enhances butyrate production by providing lactate as a metabolic substrate, thereby fostering the growth of butyrate‐producing bacteria. Butyrate plays
Rui Hua   +15 more
wiley   +1 more source

Gender Differences in Virologic Response to Treatment in an HIV-Positive Population: A Cohort Study

open access: bronze, 2001
Antonia L. Moore   +6 more
openalex   +1 more source

Toward the Clinical Translation of Implantable Brain–Computer Interfaces for Motor Impairment: Research Trends and Outcome Measures

open access: yesAdvanced Science, EarlyView.
Implantable brain–computer interfaces (iBCIs) are rapidly approaching clinical translation. This review maps key trends in the development of iBCIs and highlights the lack of standardised clinical outcome measures. It discusses a proposed framework for the selection of outcome measures in clinical trials and introduces a new international registry of ...
Esmee Dohle   +8 more
wiley   +1 more source

A Glycoproteome Data Mining Strategy for Characterizing Structural Features of Altered Glycans with Thymic Involution

open access: yesAdvanced Science, EarlyView.
This study presents a comprehensive data mining strategy for in‐depth extraction of overall and altered glycan features from structural and site‐specific glycoproteome data across various biomedical samples. The strategy enables the uncovery of four major altered glycan features associated with thymic involution and reveals their coordinated ...
Zhida Zhang   +11 more
wiley   +1 more source

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