Results 41 to 50 of about 47,177,620 (344)
Volume 11, Issue 30: September 5, 2011 [PDF]
, 2011 https://ecommons.luc.edu/wsgs_digest/1031/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
Journal of the International Association of Providers of AIDS Care, 2023 This study explored sociocultural influencers of disclosure of HIV status to children taking daily antiretroviral therapy (ART) in the Masaka region, Uganda using data collected from 26 key informant interviews with caregivers between October 2020 and ...
Robert Kairania MA +2 more
doaj +1 more source
Volume 11, Issue 23: March 28, 2011 [PDF]
, 2011 https://ecommons.luc.edu/wsgs_digest/1024/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
Volume 12, Issue 46: March 12, 2012 [PDF]
, 2012 https://ecommons.luc.edu/wsgs_digest/1047/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source
Volume 11, Issue 20: February 28, 2011 [PDF]
, 2011 https://ecommons.luc.edu/wsgs_digest/1021/thumbnail ...
Women\u27s Studies & Gender Studies Program,
core
Endocrine reviews, 2018 A sex- and gender-informed perspective increases rigor, promotes discovery, and expands the relevance of biomedical research. In the current era of accountability to present data for males and females, thoughtful and deliberate methodology can improve ...
J. Rich-Edwards +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source