Results 41 to 50 of about 2,249,772 (364)

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

The use of Qualitative Comparative Analysis (QCA) in child well-being research: a scoping review of research on child well-being research and interventions

BMC Public Health
Background Qualitative Comparative Analysis (QCA) is a method for examining configurational causality by identifying pathways that lead to an outcome of interest.
Aye Thiri Kyaw, Meghna Ranganathan, Cathy Zimmerman, Isabelle Pearson, Emily Warren, Benjamin Hanckel   +5 more
doaj   +1 more source

Caring for Women Experiencing Gender-Based Violence: A Qualitative Study from the Nursing Experience

Nursing Reports
Gender-based violence is a social problem that affects the health of women in all countries, cultures, ages and economic status; its complexity requires a transdisciplinary approach.
Meyber González-González, Venus Medina-Maldonado   +1 more
doaj   +1 more source

Human trafficking and violence: Findings from the largest global dataset of trafficking survivors

Journal of Migration and Health, 2021
Background: Human trafficking is a recognized human rights violation, and a public health and global development issue. Violence is often a hallmark of human trafficking. This study aims to describe documented cases of violence amongst persons identified
Heidi Stöckl, Camilla Fabbri, Harry Cook, Claire Galez-Davis, Naomi Grant, Yuki Lo, Ligia Kiss, Cathy Zimmerman   +7 more
doaj   +1 more source

Patriarchy and gender-inequitable attitudes as drivers of intimate partner violence against women in the central region of Ghana

BMC Public Health, 2020
Background In order to reduce women’s exposure to violence and develop culturally appropriate interventions, it is important to gain an understanding of how men who use violence rationalize it.
Y. Sikweyiya, A. Addo-Lartey, D. O. Alangea, Phyllis Dako-Gyeke, E. Chirwa, D. Coker-Appiah, R. Adanu, R. Jewkes   +7 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

The role of jealousy and infidelity in intimate partner violence against women: a qualitative meta-synthesis of five studies

BMC Public Health
Background Jealousy and infidelity are frequently identified as key drivers of intimate partner violence (IPV) yet remain underexplored in IPV prevention programming and inadequately conceptualised in measurement frameworks. This study presents the first
Marjorie Pichon, Erin Stern, Vandana Sharma, Nambusi Kyegombe, Heidi Stöckl, Ana Maria Buller   +5 more
doaj   +1 more source

Problems of legal regulation on gender-based violence in Ukraine and foreign countries

Law and Safety, 2023
The purpose of the article is to analyse gender-based violence and to study the legal mechanisms for overcoming it in Ukraine. On the basis of scientific findings and proposals, it has been suggested that a new perspective on this issue be taken.
T. S. Kyrychenko
doaj   +1 more source

Attitudes of professionals in Serbia on gender equality and gender-based violence: The research results [PDF]

Temida, 2020
In 2019 the Victimology Society of Serbia conducted the survey aimed at assessing the attitudes of professionals who work in state institutions, independent state agencies and civil society organizations in Serbia about gender equality and ...
Ćopić Sanja, Šaćiri Bejan
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source