Results 161 to 170 of about 1,127,640 (282)

Gene-Environment Interactions: Paraoxonase (PON1) and Sensitivity to Organophosphate Toxicity [PDF]

, 2006
Lucio G. Costa, Toby B. Cole, Clement E. Furlong   +2 more
openalex   +1 more source

Transcriptional regulation of neuropeptide receptors underlies context‐dependent adaptation in Drosophila melanogaster

FEBS Open Bio, EarlyView.
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu, Yanan Wei, Zekun Wu, Tianmu Zhang, DoHoon Lee, Hadi Najafi, Woo Jae Kim   +6 more
wiley   +1 more source

Gene–environment interaction between APOA5 c.553G>T and pregnancy in hypertriglyceridemia-induced acute pancreatitis

, 2020
Na Pu, Qi Yang, Xiaolei Shi, Weiwei Chen, Xiaoyao Li, Guofu Zhang, Gang Li, Baiqiang Li, Lu Ke, Zhihui Tong, D.N. Cooper, Jian‐Min Chen, Weiqin Li, Jieshou Li   +13 more
openalex   +2 more sources

Impact of Honey Bee Migratory Management on Pathogen Loads and Immune Gene Expression is Affected by Complex Interactions With Environment, Worker Life History, and Season [PDF]

, 2021
Michael Simone-Finstrom, Micheline K. Strand, David R. Tarpy, Olav Rueppell   +3 more
openalex   +1 more source

A unified model for Duchenne muscular dystrophy gene involvement in cancer: context‐dependent tumour suppression and oncogenicity

FEBS Open Bio, EarlyView.
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado, Leanne Jones, Sonika Divakar, Michael Naidoo, Karen Anthony   +4 more
wiley   +1 more source

Structural and functional characterization of chitinase from carnivorous plant Drosera adelae

FEBS Open Bio, EarlyView.
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda, Yuki Naruse, Yusaku Suizu, Tomohiro Araki, Yoshikazu Hoshi, Haruhiko Sakuraba, Junji Hayashi, Toshihisa Ohshima   +7 more
wiley   +1 more source

Pathway polygenic risk scores (pPRS) for the analysis of gene-environment interaction. [PDF]

PLoS Genet
Gauderman WJ, Fu Y, Queme B, Kawaguchi E, Wang Y, Morrison J, Brenner H, Chan A, Gruber SB, Keku T, Li L, Moreno V, Pellatt AJ, Peters U, Samadder NJ, Schmit SL, Ulrich CM, Um C, Wu A, Lewinger JP, Drew DA, Mi H.   +21 more
europepmc   +1 more source

Transcriptional regulation of proapoptotic kinase PKCδ expression in dopaminergic neurons: relevance to gene-gene and gene-environment interactions in neurodegeneration

, 2010
Huajun Jin
openalex   +2 more sources

Genes–Environment Interactions in Obesity- and Diabetes-Associated Pancreatic Cancer: A GWAS Data Analysis [PDF]

, 2013
Hongwei Tang, Peng Wei, Eric J. Duell, Harvey A. Risch, Sara H. Olson, H. Bas Bueno-de-Mesquita, Steven Gallinger, Elizabeth A. Holly, Gloria M. Petersen, Paige M. Bracci, Robert R. McWilliams, Mazda Jenab, Elio Ríboli, Anne Tjønneland, Marie‐Christine Boutron‐Ruault, Rudolf Kaaks, Dimitrios Trichopoulos, Salvatore Panico, Malin Sund, Petra H. Peeters, Kay‐Tee Khaw, Christopher I. Amos, Donghui Li   +22 more
openalex   +1 more source

Gene-by-environment interactions are pervasive among natural genetic variants

, 2023
Shi-An A. Chen, Alexander Kern, Roy Moh Lik Ang, Yihua Xie, Hunter B. Fraser   +4 more
openalex   +1 more source