Results 201 to 210 of about 1,150,120 (282)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Genome-wide association study identified novel loci and gene-environment interaction for refractive error in children. [PDF]

NPJ Genom Med
Wang Y, Zhang Y, Chen H, Zhang XJ, Zhang R, Ng TK, Tham JA, Kam KW, Tam POS, Young AL, Wei Y, Zhang M, Pang CP, Tham CC, Yam JC, Chen LJ.   +15 more
europepmc   +1 more source

Gene-environment interaction study on the polygenic risk score for neuroticism, childhood adversity, and parental bonding. [PDF]

Personal Neurosci, 2023
Klingenberg B, Guloksuz S, Pries LK, Cinar O, Menne-Lothmann C, Decoster J, van Winkel R, Collip D, Delespaul P, De Hert M, Derom C, Thiery E, Jacobs N, Wichers M, Lin BD, Luykx J, van Os J, Rutten BPF.   +17 more
europepmc   +1 more source

Genotype by environment interactions in gene regulation underlie the response to soil drying in the model grass Brachypodium distachyon [PDF]

Jie Yun, Angela C. Burnett, Alistair Rogers, David L. Des Marais   +3 more
openalex   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Gene-environment interaction modifies the association between hyperinsulinemia and serum urate levels through SLC22A12. [PDF]

J Clin Invest
Fujii W, Yamazaki O, Hirohama D, Kaseda K, Kuribayashi-Okuma E, Tsuji M, Hosoyamada M, Kochi Y, Shibata S.   +8 more
europepmc   +1 more source

The oxytocin receptor rs2254298 polymorphism and alcohol withdrawal symptoms: a gene-environment interaction in mood disorders. [PDF]

Front Psychiatry, 2023
Shen G, Yang S, Wu L, Chen Y, Hu Y, Zhou F, Wang W, Liu P, Wu F, Liu Y, Wang F, Chen L.   +11 more
europepmc   +1 more source

ReninAngiotensinAldosterone System Gene Polymorphisms and Coronary Artery Disease: Detection of Gene-Gene and Gene-Environment Interactions

, 2012
En‐Zhi Jia, Zhenxia Xu, Chang–Yan Guo, Li Li, Yan Gu, Tiebing Zhu, Lian‐Sheng Wang, Kejiang Cao, Wen‐Zhu Ma, Zhijian Yang   +9 more
openalex   +1 more source

Gene-Environment Interaction: Definitions and Study Designs [PDF]

, 2008
Ruth Ottman, Ruth Ottman
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source