Results 161 to 170 of about 6,429,624 (316)

Man turning a valve wheel to adjust the flow of water to the pelton wheel turbine. He is looking towards a group of meters on an electricity cabinet on the wall.

open access: yes, 2015
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Detail of a quite big steel inlet pipe and flanges of a pelton wheel turbine. Also visible are hydraulicly operated flow valve actuators.

open access: yes, 2015
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Action for Soviet Jewry events (110 digital images)

open access: yes
Action for Soviet Jewry events: Avital Sharansky with Governor Dukakis; Action for Soviet Jewry events, including Soviet Jewry Culture Cruise and photographs with R. Gordon, R. Drinan, Lynn Singer, Refuseniks Kornfeld, Branover. and Bayard Rustin.Digital
Action for Soviet Jewry
core  

Newly installed pelton wheel hydro electric turbine, showing flow control valve and generator.

open access: yes, 2015
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Man flattening render he has applied to the wallins of a new power house.

open access: yes, 2015
The Eastern slopes of the Andes in North Peru are among the least developed parts of the country with the majority of people living in remote villages with little or no access to grid electricity.
Practical Action Peru
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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