UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro +7 more
wiley +1 more source
Decoding the genetic basis of demyelination: Prediction of potential pathogenic coding and regulatory noncoding MBP SNPs in multiple sclerosis. [PDF]
Alwabran AI +5 more
europepmc +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
multiHIVE: Hierarchical Multimodal Deep Generative Modeling for Single-cell Multiomics
Nanduri A, Pavan MK, Pandey K, Zafar H.
europepmc +1 more source
Climate-Induced Genomic Selection: Genetic Structure Variation of <i>Cornus kousa</i> subsp. <i>chinensis</i> and Its Adaptive Reaction to Future Climate Change. [PDF]
Li J, Liu Q, Gong X, Ruan L, Guan B.
europepmc +1 more source
Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai +18 more
wiley +1 more source
Conservation Hotspots of <i>Quercus castaneifolia</i> Revealed Through the Integration of Genetic Diversity and Landscape Connectivity. [PDF]
Shahnaseri G +3 more
europepmc +1 more source
The Iceman's microbiome: unveiling millennia of microbial diversity and continuity. [PDF]
Sarhan MS +3 more
europepmc +1 more source
The complete mitochondrial genome of <i>Morbakka virulenta</i> Kishinouyea, 1910 (Cnidaria: Cubozoa: Carybdeida). [PDF]
Tian J +6 more
europepmc +1 more source

