Results 171 to 180 of about 7,960,154 (346)

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Gene conversion: a non-Mendelian process integral to meiotic recombination. [PDF]

Heredity (Edinb), 2022
Lorenz A, Mpaulo SJ.
europepmc   +1 more source

SELECTION AND BIASED GENE CONVERSION IN A MULTIGENE FAMILY: CONSEQUENCES OF INTERALLELIC BIAS AND THRESHOLD SELECTION [PDF]

, 1986
James Bruce Walsh
openalex   +1 more source

Endoglin mediates the tumor‐ and metastasis‐promoting traits of stromal myofibroblasts in human breast carcinomas

Molecular Oncology, EarlyView.
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo, Yoshihiro Mezawa, Zixu Wang, Ahmet Acar, Yasuhiko Ito, Atsushi Takano, Yohei Miyagi, Tomoyuki Yokose, Toshinari Yamashita, Yataro Daigo, Takuya Shirakihara, Akira Orimo   +11 more
wiley   +1 more source

CRISPR/Cas9-induced gene conversion between ATAD3 paralogs. [PDF]

HGG Adv, 2022
Yanovsky-Dagan S, Frumkin A, Lupski JR, Harel T.   +3 more
europepmc   +1 more source

Gene conversion, linkage, and the evolution of multigene families. [PDF]

, 1988
Thomas Nagylaki
openalex   +1 more source

Gene conversion in mitochondria [PDF]

Nature, 1978
openaire   +2 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Possible biased virulence attenuation in the Senegal strain of Ehrlichia ruminantium by ntrX gene conversion from an inverted segmental duplication. [PDF]

PLoS One, 2023
Gordon JL, Oliva Chavez AS, Martinez D, Vachiery N, Meyer DF.   +4 more
europepmc   +1 more source

Mitotic Gene Conversion Lengths, Coconversion Patterns, and the Incidence of Reciprocal Recombination in a Saccharomyces cerevisiae Plasmid System [PDF]

, 1986
Byung‐Yoon Ahn, Dennis Livingston
openalex   +1 more source