Analysis of the recombination landscape of hexaploid bread wheat reveals genes controlling recombination and gene conversion frequency [PDF]
Genome Biology, 2019 Sequence exchange between homologous chromosomes through crossing over and gene conversion is highly conserved among eukaryotes, contributing to genome stability and genetic diversity.
Laura-Jayne Gardiner +10 more
semanticscholar +3 more sources
Gene conversion in human rearranged immunoglobulin genes [PDF]
Immunogenetics, 2006 Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V(H) segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these is very similar to primary V(D)J recombination, involving the RAG proteins acting upon recombination signal sequences ...
Darlow, J.M., Stott, D.I.
openaire +5 more sources
Recombination Dynamics of a Human Y-Chromosomal Palindrome: Rapid GC-Biased Gene Conversion, Multi-kilobase Conversion Tracts, and Rare Inversions [PDF]
PLoS Genetics, 2013 The male-specific region of the human Y chromosome (MSY) includes eight large inverted repeats (palindromes) in which arm-to-arm similarity exceeds 99.9%, due to gene conversion activity.
P. Hallast +4 more
semanticscholar +5 more sources
High-resolution mapping of heteroduplex DNA formed during UV-induced and spontaneous mitotic recombination events in yeast [PDF]
eLife, 2017 In yeast, DNA breaks are usually repaired by homologous recombination (HR). An early step for HR pathways is formation of a heteroduplex, in which a single-strand from the broken DNA molecule pairs with a strand derived from an intact DNA molecule.
Yi Yin +3 more
doaj +5 more sources
A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes [PDF]
PLoS Genetics, 2013 GC-biased gene conversion (gBGC) is a recombination-associated process that favors the fixation of G/C alleles over A/T alleles. In mammals, gBGC is hypothesized to contribute to variation in GC content, rapidly evolving sequences, and the fixation of ...
J. Capra +4 more
semanticscholar +9 more sources
Patterns of Inter-Chromosomal Gene Conversion on the Male-Specific Region of the Human Y Chromosome [PDF]
Frontiers in Genetics, 2017 The male-specific region of the human Y chromosome (MSY) is characterized by the lack of meiotic recombination and it has long been considered an evolutionary independent region of the human genome.
Beniamino Trombetta +3 more
doaj +3 more sources
Conversion events in gene clusters [PDF]
BMC Evolutionary Biology, 2011 Background Gene clusters containing multiple similar genomic regions in close proximity are of great interest for biomedical studies because of their associations with inherited diseases.
Hardison Ross C +9 more
doaj +3 more sources
Estimating Gene Conversion Tract Length and Rate From PacBio HiFi Data. [PDF]
Mol Biol EvolCharmouh AP +8 more
europepmc +3 more sources
Plant organellar genomes utilize gene conversion to drive heteroplasmic sorting. [PDF]
Proc Natl Acad Sci U S A, 2022 Schaffner SH, Patel MR.
europepmc +3 more sources
GC-biased gene conversion in X-chromosome palindromes conserved in human, chimpanzee, and rhesus macaque [PDF]
G3: Genes, Genomes, Genetics, 2021 Gene conversion is GC-biased across a wide range of taxa. Large palindromes on mammalian sex chromosomes undergo frequent gene conversion that maintains arm-to-arm sequence identity greater than 99%, which may increase their susceptibility to the effects
Emily K Jackson +3 more
doaj +2 more sources