Efficient GBA1 editing via HDR with ssODNs by outcompeting pseudogene-mediated gene conversion upon CRISPR/Cas9 cleavage. [PDF]
Lagas JS, Sentmanat MF, Cui X.
europepmc +1 more source
New insights into the evolution of human Y chromosome palindromes through mutation and gene conversion. [PDF]
Bonito M +7 more
europepmc +1 more source
Evidence for intrachromosomal gene conversion in cultured mouse cells
R. Michael Liskay, Janet L. Stachelek
openalex +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Long-read sequencing identifies copy-specific markers of SMN gene conversion in spinal muscular atrophy. [PDF]
Zwartkruis MM +19 more
europepmc +1 more source
Sgs1 Regulates Gene Conversion Tract Lengths and Crossovers Independently of Its Helicase Activity
Yi‐Chen Lo +6 more
openalex +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Genomics of natural populations: gene conversion events reveal selected genes within the inversions of Drosophila pseudoobscura. [PDF]
Schaeffer SW, Richards S, Fuller ZL.
europepmc +1 more source
Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair. [PDF]
Wilde JJ +8 more
europepmc +1 more source

