Genomics of natural populations: gene conversion events reveal selected genes within the inversions of Drosophila pseudoobscura. [PDF]
Schaeffer SW, Richards S, Fuller ZL.
europepmc +1 more source
Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair. [PDF]
Wilde JJ +8 more
europepmc +1 more source
SmallTalk: a novel small‐sized fusion tag for peptide expression and purification
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq +3 more
wiley +1 more source
Biobank-scale inference of multi-individual identity by descent and gene conversion. [PDF]
Browning SR, Browning BL.
europepmc +1 more source
Autophagosome marker, LC3, is released extracellularly via several distinct pathways
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Intermolecular Gene Conversion for the Equalization of Genome Copies in the Polyploid Haloarchaeon Haloferax volcanii: Identification of Important Proteins. [PDF]
Özer H, Wasser D, Sandner L, Soppa J.
europepmc +1 more source
The ERCC1/XPF endonuclease is required for efficient single-strand annealing and gene conversion in mammalian cells [PDF]
A. Z. Al-Minawi +2 more
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DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Efficient antibody diversification by gene conversion in vivo in the absence of selection for V(D)J-encoded determinants [PDF]
Camil E. Sayegh +2 more
openalex +1 more source

