CRISPR/Cas9-induced gene conversion between ATAD3 paralogs [PDF]
HGG Advances, 2022 Paralogs and pseudogenes are abundant within the human genome, and can mediate non-allelic homologous recombination (NAHR) or gene conversion events.
Shira Yanovsky-Dagan +3 more
doaj +2 more sources
The Putative Endonuclease Activity of MutL Is Required for the Segmental Gene Conversion Events That Drive Antigenic Variation of the Lyme Disease Spirochete [PDF]
Frontiers in Microbiology, 2022 The Lyme disease spirochete Borrelia burgdorferi, encodes an elaborate antigenic variation system that promotes the ongoing variation of a major surface lipoprotein, VlsE.
Mildred Castellanos +4 more
doaj +2 more sources
Gene conversion-associated successive engineering of modular polyketide synthases. [PDF]
Commun ChemJin W, Tu J, Zhang B, Wu X, Chen Y.
europepmc +3 more sources
Chromatin structure regulates gene conversion. [PDF]
PLoS Biology, 2007 Homology-directed repair is a powerful mechanism for maintaining and altering genomic structure. We asked how chromatin structure contributes to the use of homologous sequences as donors for repair using the chicken B cell line DT40 as a model.
W Jason Cummings +5 more
doaj +3 more sources
Conversion events in gene clusters [PDF]
BMC Evolutionary Biology, 2011 Background Gene clusters containing multiple similar genomic regions in close proximity are of great interest for biomedical studies because of their associations with inherited diseases.
Hardison Ross C +9 more
doaj +3 more sources
Estimating Gene Conversion Tract Length and Rate From PacBio HiFi Data. [PDF]
Mol Biol EvolCharmouh AP +8 more
europepmc +3 more sources
Gene conversion in the rice genome [PDF]
BMC Genomics, 2008 Background Gene conversion causes a non-reciprocal transfer of genetic information between similar sequences. Gene conversion can both homogenize genes and recruit point mutations thereby shaping the evolution of multigene families.
Vang Søren +7 more
doaj +10 more sources
Stop Codon Usage as a Window into Genome Evolution: Mutation, Selection, Biased Gene Conversion and the TAG Paradox. [PDF]
Genome Biol Evol, 2022 Ho AT, Hurst LD.
europepmc +3 more sources
The Interspecific Fungal Hybrid
mBio, 2021 Hybridization is an important evolutionary mechanism that can enable organisms to adapt to environmental challenges. It has previously been shown that the fungal allodiploid species Verticillium longisporum, the causal agent of verticillium stem striping
Jasper R. L. Depotter +9 more
doaj +3 more sources
Gene Conversion Facilitates the Adaptive Evolution of Self-Resistance in Highly Toxic Newts. [PDF]
Mol Biol Evol, 2021 Gendreau KL +3 more
europepmc +3 more sources