Results 51 to 60 of about 8,369,274 (283)
Patterns of gene conversion in duplicated yeast histones suggest strong selection on a coadapted macromolecular complex [PDF]
, 2015 We find evidence for interlocus gene conversion in five duplicated histone genes from six yeast species. The sequences of these duplicated genes, surviving from the ancient genome duplication, show phylogenetic patterns inconsistent with the well ...
Conant, Gavin C +2 more
core +2 more sources
Gene Duplication and Ectopic Gene Conversion in Drosophila [PDF]
Genes, 2011 The evolutionary impact of gene duplication events has been a theme of Drosophila genetics dating back to the Morgan School. While considerable attention has been placed on the genetic novelties that duplicates are capable of introducing, and the role that positive selection plays in their early stages of duplicate evolution, much less attention has ...
J. Roman Arguello, Tim Connallon
openaire +3 more sources
Frontiers in Immunology, 2018 An important characteristic of chickens is that the antibody repertoire is based on a single framework, with diversity found mainly in the CDRs of the light and heavy chain variable regions.
Philip A. Leighton +3 more
doaj +1 more source
The rate of meiotic gene conversion varies by sex and age
Nature Genetics, 2016 Meiotic recombination involves a combination of gene conversion and crossover events that, along with mutations, produce germline genetic diversity. Here we report the discovery of 3,176 SNP and 61 indel gene conversions.
B. Halldórsson +15 more
semanticscholar +1 more source
Sequence of the mouse Q4 class I gene and characterization of the gene product [PDF]
, 1988 The Q4 class I gene has been shown to participate in gene conversion events within the mouse major histocompatibility complex. Its complete genomic nucleotide sequence has been determined.
Bevec, Dorian +3 more
core +1 more source
hagis, an R Package Resource for Pathotype Analysis of Phytophthora sojae Populations Causing Stem and Root Rot of Soybean [PDF]
, 2019 Phytophthora sojae is a significant pathogen of soybean worldwide. Pathotype surveys for Phytophthora sojae are conducted to monitor resistance gene efficacy and determine if new resistance genes are needed.
Chilvers, Martin +3 more
core +2 more sources
Tetrad analysis in plants and fungi finds large differences in gene conversion rates but no GC bias
Nature Ecology & Evolution, 2017 GC-favouring gene conversion enables fixation of deleterious alleles, disturbs tests of natural selection and potentially explains both the evolution of recombination as well as the commonly reported intragenomic correlation between G+C content and ...
Haoxuan Liu +9 more
semanticscholar +1 more source
Pyrosequencing Evaluation of Widely Available Bisulfite Conversion Methods: Considerations for Application [PDF]
, 2014 Introduction: Bisulfite treatment of DNA introduces methylation-dependent sequence changes through selective chemical conversion of nonmethylated cytosine to uracil and serves as pretreatment step for the majority of DNA methylation analysis methods ...
Binder, Alexandra M. +2 more
core +3 more sources
Mechanisms of Ectopic Gene Conversion [PDF]
Genes, 2010 Gene conversion (conversion), the unidirectional transfer of DNA sequence information, occurs as a byproduct of recombinational repair of broken or damaged DNA molecules. Whereas excision repair processes replace damaged DNA by copying the complementary sequence from the undamaged strand of duplex DNA, recombinational mechanisms copy similar sequence ...
openaire +2 more sources
Nature Communications, 2020 Huntington’s disease (HD) is caused by Huntingtin (Htt) gene mutation resulting in the loss of striatal GABAergic neurons and motor functional deficits. We report here an in vivo cell conversion technology to reprogram striatal astrocytes into GABAergic ...
Zheng Wu +10 more
semanticscholar +1 more source