Results 171 to 180 of about 189,147 (282)

Integrating mosquito genomics into simulation modeling: opportunities for better-informed biocontrol. [PDF]

Curr Opin Insect Sci
Rašić G, Marshall JM.
europepmc   +1 more source

The Genomic Arms Race in Mosquito-Borne Diseases: Integrating Entomopathogenic Fungi, Gene Drive, and Symbiont Technologies for Sustainable Vector Control

R Yamini, Pagalahalli Sankaran Shanmugam, M. Murugan, N. Geetha, Subramanian Jeyarani, Rajasekaran Raghu, Subramanian Marimuthu   +6 more
openalex   +1 more source

Non-human primate models and multimodal technologies synergistically drive translational breakthroughs in gene therapy for optic nerve diseases [PDF]

Jian Wu
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Utility of Tumor Suppressor E2F Target Gene Promoter Elements to Drive Gene Expression Specifically in Cancer Cells. [PDF]

Cells
Kurayoshi K, Tanaka M, Nakajima R, Zhou Y, Shirasawa M, Fikriyanti M, Fujisawa JI, Iwanaga R, Bradford AP, Araki K, Ohtani K.   +10 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Assessing target genes for homing suppression gene drive. [PDF]

EMBO J
Xu X, Fang J, Chen J, Yang J, Yang X, Hou S, Sun W, Champer J.   +7 more
europepmc   +1 more source

PLOS Science Wednesday: Hi reddit, I’m Jackson and I identified an important barrier to the practical application of gene drives using CRISPR/Cas9 technology, which could be used to fight vector-borne diseases like malaria – Ask Me Anything! [PDF]

, 2017
PLOSScienceWednesday, r Science
openalex   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Editorial for Special Issue "Linking Genomic Changes with Cancer in the NGS Era, 2nd Edition". [PDF]

Curr Issues Mol Biol
Azúa-Romeo J.
europepmc   +1 more source