Results 261 to 270 of about 199,466 (296)

Deciphering copy number variations and gene implications in an Egyptian cohort with autism spectrum disorders. [PDF]

open access: yesBMC Med Genomics
Mohamed AM   +10 more
europepmc   +1 more source

Evolution of Duplicated Hox Gene Clusters in Land Snails and Slugs. [PDF]

open access: yesJ Exp Zool B Mol Dev Evol
McHale F, Mulhair PO, Holland PWH.
europepmc   +1 more source

Complex de novo structural variants are an underestimated cause of rare disorders. [PDF]

open access: yesNat Commun
Jung H   +12 more
europepmc   +1 more source

Genome Distance and Phylogenetic Inference Accommodating Gene Duplication, Loss and New Gene Input

Molecular Phylogenetics and Evolution, 2023
With the rapid growth of entire genome data, phylogenomics focuses on analyzing evolutionary histories and relationships of species, i.e., the tree of life. For decades it has been realized that the genome-wide phylogenetic inference can be approached based upon the dynamic pattern of gene content (the presence/absence of gene families), or extended ...
openaire   +2 more sources

Evolution of Gene Families Based on Gene Duplication, Loss, Accumulated Change, and Innovation

Journal of Computational Biology, 2007
We introduce and analyze a simple discrete probabilistic model of genome evolution. It is based on four fundamental evolutionary events: gene duplication, loss, accumulated change and innovation. We call it the DLCI model. It is the first such model rigorously analyzed. The focus of the paper is on the size distribution of gene families.
Damian, Wójtowicz, Jerzy, Tiuryn
openaire   +2 more sources

Mean Values of Gene Duplication and Loss Cost Functions

2016
Reconciliation based cost functions play crucial role in comparing gene family trees with their species tree. To provide a better understanding of tree reconciliation we derive mean formulas for gene duplication, gene loss and gene duplication-loss cost functions, for a fixed species tree under the uniform model of gene trees.
Paweł Górecki   +2 more
openaire   +1 more source

Reconciliation problems for duplication, loss and horizontal gene transfer

Proceedings of the eighth annual international conference on Computational molecular biology - RECOMB '04, 2004
This paper presents a model of reconciling a species tree and a gene tree in an extended duplication-loss model. In the first part the definition of a model is introduced. In the second the horizontal transfer is defined and a new polynomial reconciliation algorithm is presented.
openaire   +1 more source

Protein polymorphism and the rate of loss of duplicate gene expression

Nature, 1978
THE adaptive significance of the widespread protein polymorphism found in natural populations continues to be a central issue in population genetics1–3. Whether this variation is maintained by some form of balancing selection (the selectionist hypothesis) or by the stochastic interaction between selectively neutral mutations and genetic drift (the ...
openaire   +2 more sources

Home - About - Disclaimer - Privacy