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Messy Genetic Algorithm for evolving mathematical function evaluating variable length gene regulatory networks

2013 IEEE Congress on Evolutionary Computation, 2013
Evolutionary algorithms (EAs) have been successfully used in many studies for evolving both the structure and parameters of biological networks including gene regulatory networks that demonstrate different functionalities. However, most of these studies have used only mutation as the genetic operator in the evolutionary framework, perhaps due to the ...
Dhammika S. Hettiarachchi   +2 more
openaire   +1 more source

Abstract 4852: Performances evaluation of algorithms for identifying differentially expressed genes in RNA-seq data

Cancer Research, 2015
Abstract Introduction RNA sequencing (RNA-seq) has rapidly become one of the main methods to study transcriptome. It has become an important and popular issue to identify biomarkers based on their differential expression patterns in NGS data. Currently, more than 10 different algorithms can be used to detect differentially
Chin-Ting Wu   +4 more
openaire   +1 more source

Evaluating Hyperparameter Optimization in Machine Learning Algorithms for Cancer Driver Gene Classification

Anais da I Escola Regional de Aprendizado de Máquina e Inteligência Artificial da Região Sul (ERAMIA-RS 2025)
Cancer driver genes (CDGs) play a central role in tumorigenesis and represent important targets for diagnosis and therapy. In this study, we evaluate the impact of hyperparameter optimization on the predictive performance of traditional machine learning algorithms using multi-omics data. We perform systematic searches across different configurations to
Ana Laura Schardosim   +3 more
openaire   +1 more source

Deconer: A comprehensive and systematic evaluation toolkit for reference-based cell type deconvolution algorithms using gene expression data

2023
Abstract In recent years, computational methods for quantifying cell type proportions from transcription data have gained significant attention, particularly those reference-based methods which have demonstrated high accuracy. However, there is currently a lack of comprehensive evaluation and guidance for available reference-based ...
Wei Zhang   +7 more
openaire   +1 more source

Evaluation and Improving Hypergraph Based Learning Algorithm over Data Integration Problem for Cancer Related Genes

2012 International Conference on Advances in Computing and Communications, 2012
Reliable predictive model build using semi supervised learning utilising classification algorithm has evolved rapidly in successful cancer treatment. In order to optimise the data integration problem, such as hypergraph based learning to integrate microarray gene expressions and protein interactions for predicting cancer outcome, novice optimization ...
Seena Mary Augusty, Sminu Izudheen
openaire   +1 more source

Performance Evaluation of Subspace-based Algorithm in Selecting Differentially Expressed Genes and Classification of Tissue Types from Microarray Data

The 2006 IEEE International Joint Conference on Neural Network Proceedings, 2006
This paper presents the implementation and evaluation of subspace-based clustering algorithm for robust selection of differentially expressed genes as well as the classification of tissue types from microarray data. The performance of the proposed algorithm is compared against other well known clustering algorithms and the quality of clusters is ...
Jahangheer S. Shaik, Mohammed Yeasin
openaire   +1 more source

Extending meta-learning framework for clustering gene expression data with component-based algorithm design and internal evaluation measures

International Journal of Data Mining and Bioinformatics, 2016
Class retrieval in gene expression microarray data analysis is highly challenging task. Because of high class imbalance, highly dimensional feature space and small number of samples most of the algorithms fail to capture real complex structures in data 'golden standard'.
Milan Vukicevic   +3 more
openaire   +2 more sources

Examing and Evaluating Dimension Reduction Algorithms for Classifying Alzheimer’s Diseases using Gene Expression Data

2021 17th International Conference on Mobility, Sensing and Networking (MSN), 2021
Shunbao Li   +2 more
openaire   +1 more source

Gene expression programming algorithm based on multi-threading evaluator

Journal of Computer Applications, 2013
Sheng-qiao NI   +3 more
openaire   +1 more source

Gene selection and classification of microarray data method based on mutual information and moth flame algorithm.

Expert Systems With Applications, 2021
Ali Dabba   +2 more
exaly  

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