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DNA Supercoiling as a Regulator of Bacterial Gene Expression
1987Studies of gene expression have advanced to a stage at which we can ask quite detailed questions about the factors that influence transcription and the ways in which these factors interact with each other. Such factors include not only the specific proteins that bind to regulatory sites on DNA, but also more subtle aspects of DNA structure, such as ...
Martin Gellert, Rolf Menzel
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Regulation of Bacterial Gene Expression
1989The total properties of any bacterium result from an interplay between its genome and its environment. The bacterium Escherichia coli carries approximately 3000 genes, but this total repertoire describes its potential properties and, in reality, only a small subset of this genetic information is expressed at any given moment. A primary influence of the
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Regulation of Expression of Bacterial Genes in the Absence of Active Cell Growth
Russian Journal of Genetics, 2005Global changes in cell physiology and metabolism take place in bacterial cells entering the stationary phase. The processes that ensure cell survival under adverse environmental conditions are activated, and cells with an improved resistance to many stress factors are formed as a result of the general stress response. The review considers the molecular
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Regulation of Bacterial Gene Expression by Protease-Alleviated Spatial Sequestration (PASS)
ACS Synthetic Biology, 2015In natural microbial systems, conditional spatial sequestration of transcription factors enables cells to respond rapidly to changes in their environment or intracellular state by releasing presynthesized regulatory proteins. Although such a mechanism may be useful for engineering synthetic biology technologies ranging from cell-based biosensors to ...
Ragan A, Pitner +2 more
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Bacterial lipases from Pseudomonas: Regulation of gene expression and mechanisms of secretion
Biochimie, 2000Lipases from Pseudomonas bacteria are widely used for a variety of biotechnological applications. Overexpression in heterologous hosts like Escherichia coli failed to produce enzymatically active lipase prompting to study the molecular mechanisms underlying the regulation of lipase gene expression and secretion. The prototype lipase from P.
F, Rosenau, K, Jaeger
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The role of mRNA degradation in the regulated expression of bacterial photosynthesis genes
Molecular Microbiology, 1993SummaryRegulation of gene expression in bacteria, as in eukaryotic cells, is often achieved by variation of mRNA levels. Since the steady state levels of mRNA depend on both the rate of synthesis and the rate of decay, both mechanisms are important for gene regulation. After considerable effort undertaken over many years to understand the regulation of
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Bacterial Aminoacyl-tRNA Synthetases: Genes and Regulation of Expression
2014Aminoacyl-tRNA synthetases (AARS) form a class of essential enzymes whose main role is to ligate amino acids to tRNAs. This chapter reviews what is known about the AARS genes, their chromosomal localization, their organization, and the regulation of their expression.
Harald Putzer +2 more
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Molecular Microbiology, 1990
SummaryThere has been a recent revival of interest in one of the most abundant Escherichia coli proteins, H1 (also called H‐NS). This protein was first identified many years ago as a major component of the bacterial nucleoid, and has been characterized biochemically by several groups.
Higgins, C. F. +5 more
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SummaryThere has been a recent revival of interest in one of the most abundant Escherichia coli proteins, H1 (also called H‐NS). This protein was first identified many years ago as a major component of the bacterial nucleoid, and has been characterized biochemically by several groups.
Higgins, C. F. +5 more
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Cell, 1984
A naturally occurring small RNA molecule ( micF RNA), complementary to the region encompassing the Shine-Dalgarno sequence and initiation codon of the ompF mRNA, is known to block the expression of that mRNA in E. coli. We have constructed a plasmid that produces a complementary RNA to the E. coli lpp mRNA (mic[Ipp] RNA). Induction of the mic(Ipp) gene
J, Coleman, P J, Green, M, Inouye
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A naturally occurring small RNA molecule ( micF RNA), complementary to the region encompassing the Shine-Dalgarno sequence and initiation codon of the ompF mRNA, is known to block the expression of that mRNA in E. coli. We have constructed a plasmid that produces a complementary RNA to the E. coli lpp mRNA (mic[Ipp] RNA). Induction of the mic(Ipp) gene
J, Coleman, P J, Green, M, Inouye
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Multilevel Regulation of Bacterial Gene Expression with the Combined STAR and Antisense RNA System
ACS Synthetic Biology, 2018Synthetic small RNA regulators have emerged as a versatile tool to predictably control bacterial gene expression. Owing to their simple design principles, small size, and highly orthogonal behavior, these engineered genetic parts have been incorporated into genetic circuits.
Young Je Lee +2 more
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