Results 281 to 290 of about 1,053,006 (335)

Regulation of bacterial gene expression by riboswitches.

Annual Review of Microbiology, 2005
Riboswitches are structured domains that usually reside in the noncoding regions of mRNAs, where they bind metabolites and control gene expression. Like their protein counterparts, these RNA gene control elements form highly specific binding pockets for the target metabolite and undergo allosteric changes in structure. Numerous classes of riboswitches
W. Winkler, R. Breaker
semanticscholar   +4 more sources

Regulation of gene expression in mouse macrophages stimulated with bacterial CpG‐DNA and lipopolysaccharide

Journal of Leukocyte Biology, 2002
CpG‐DNA is known as a potent immunostimulating agent and may contribute in therapeutic treatment of many immune disorders. CpG‐DNA triggers innate and acquired immune responses through activated expression of various genes in immune cells, including ...
J. Gao, Veronica Diesl, Tatiana Wittmann, D. Morrison, J. Ryan, S. Vogel, M. Follettie   +6 more
semanticscholar   +4 more sources

Regulation of bacterial gene expression by metal–protein complexes

Molecular Microbiology, 1990
SummaryMetal ions are essential cofactors in several transacting bacterial gene regulators. Upon binding of the metal, the receptor proteins act either as repressors of gene expression or, in other systems, as transcriptional activators. Other metal‐dependent regulatory proteins may function, directly or indirectly, as sensors of the cellular oxygen ...
Hauke Hennecke
semanticscholar   +4 more sources

CRISPR Interference in Regulation of Bacterial Gene Expression

Molecular Biology, 2022
The review is devoted to the use of the CRISPR/Cas system for obtaining knockdowns of target bacterial genes by CRISPR-mediated interference (CRISPRi). CRISPRi is based on the preservation of the ability of the inactivated dCas nuclease in complex with guide RNA to bind a target, which leads to reversible repression of the selected genes.
N I, Nadolinskaia, A V, Goncharenko
openaire   +2 more sources

Regulation of Bacterial Gene Expression

, 1989
The total properties of any bacterium result from an interplay between its genome and its environment. The bacterium Escherichia coli carries approximately 3000 genes, but this total repertoire describes its potential properties and, in reality, only a small subset of this genetic information is expressed at any given moment. A primary influence of the
W. Reznikoff
semanticscholar   +3 more sources

Multilevel Regulation of Bacterial Gene Expression with the Combined STAR and Antisense RNA System.

ACS Synthetic Biology, 2018
Synthetic small RNA regulators have emerged as a versatile tool to predictably control bacterial gene expression. Owing to their simple design principles, small size, and highly orthogonal behavior, these engineered genetic parts have been incorporated into genetic circuits.
Young Je Lee, Soo-Jung Kim, T. Moon
semanticscholar   +3 more sources

Regulation of bacterial gene expression in response to oxidative stress.

Methods in Enzymology, 1994
Publisher Summary This chapter presents the approaches used to study the regulation of oxidative defense genes in Escherichia coli and Salmonella typhimurium . These general approaches should be useful in examining the response to oxidative stress in other organisms and in further elucidating the response in E. coli and S. typhimurium .
G. Storz, M. Tolédano
semanticscholar   +4 more sources

Temperature-regulated expression of bacterial virulence genes

Microbes and Infection, 2000
Virulence gene expression in most bacteria is a highly regulated phenomenon, affected by a variety of parameters including osmolarity, pH, ion concentration, iron levels, growth phase, and population density. Virulence genes are also regulated by temperature, which acts as an 'on-off' switch in a manner distinct from the more general heat-shock ...
Michael E. Konkel, Kit Tilly
openaire   +3 more sources