Results 231 to 240 of about 1,946,714 (353)

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Gene flow and differential mortality in a contact zone between two Albinaria species (Gastropoda; Clausiliidae) [PDF]

, 2000
Sinos Giokas, Moysis Mylonas, Konstantinos Sotiropoulos   +2 more
openalex   +1 more source

Long-distance gene flow and recombination shape the evolutionary history of a maize pathogen. [PDF]

IMA Fungus
Rogério F, Van Oosterhout C, De Mita S, Cuevas-Fernández FB, García-Rodríguez P, Becerra S, Gutiérrez-Sánchez S, Jacquat AG, Bettiol W, Hosaka GK, Ulla SB, Hiltbrunner J, Santiago R, Revilla P, Dambolena JS, Vicente-Villardón JL, Buhiniček I, Sukno SA, Thon MR.   +18 more
europepmc   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

On the relation between gene flow theory and genetic gain [PDF]

, 2000
Piter Bijma, John Woolliams
openalex   +1 more source

Resolving phylogenetic conflicts in Pandanales: the dual roles of gene flow and whole-genome duplication. [PDF]

Front Plant Sci
Shi T, He J.
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

BARRIERS TO GENE FLOW INEMBIOTOCA JACKSONI, A MARINE FISH LACKING A PELAGIC LARVAL STAGE [PDF]

, 2000
Giacomo Bernardi
openalex   +1 more source

Multiple Origins or Widespread Gene Flow in Agricultural Fields? Regional Population Genomics of Herbicide Resistance in Bromus tectorum. [PDF]

Mol Ecol
Ribeiro VHV, Gallagher J, Mallory-Smith C, Barroso J, Brunharo CACG.   +4 more
europepmc   +1 more source

A DIA‐MS‐based proteomics approach to find potential serum prognostic biomarkers in glioblastoma patients

Molecular Oncology, EarlyView.
A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul, François Guillonneau, Odile Blanchet, Hamza Lasla, Audrey Rousseau, Catherine Guette, Alice Boissard, Cécile Henry, Morgan Dhondt, Pascal Jézéquel, Philippe Menei, Jean‐Michel Lemée   +11 more
wiley   +1 more source