Results 141 to 150 of about 1,747,624 (329)
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Molecular Oncology, EarlyView.Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi +6 more
wiley +1 more source
Gene frequency and haplotype analysis of HLA class I in patients with simple renal cysts
مجله كليه طب الكندي, 2015 Background: The study of human leukocytes (HLA) alleles, and haplotype frequencies within populations provide an important source of information for anthropological investigation, organ and hematopoietic stem cell transplantation as well as disease ...
Aroub A.R Al-kaisi +2 more
doaj
Genes that modulate the frequency of mutation at meiosis [PDF]
Experimental & Molecular Medicine, 2018 Hunter, Ronald H.F., Einer-Jensen, Niels
openaire +4 more sources
Molecular Oncology, EarlyView.This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke +12 more
wiley +1 more source
Diploid populations with selection depending on gene frequency [PDF]
, 1963 Warren J. Ewens
openalex +1 more source
Molecular Oncology, EarlyView.We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić +31 more
wiley +1 more source
Spatial Gene Frequency Waves Under Genotype-Dependent Dispersal. [PDF]
Genetics, 2017 Novak S, Kollár R.
europepmc +1 more source
ON THE ROLES OF DIRECTED AND RANDOM CHANGES IN GENE FREQUENCY IN THE GENETICS OF POPULATIONS
, 1948 Sewall Wright
openalex +1 more source
FREQUENCY-DEPENDENT SELECTION FOR THE DOMINANCE OF RARE POLYMORPHIC GENES [PDF]
, 1964 Bryan Clarke
openalex +1 more source
Molecular Oncology, EarlyView.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source