Results 151 to 160 of about 13,063,295 (390)

Gene frequency and haplotype analysis of HLA class I in patients with simple renal cysts

مجله كليه طب الكندي, 2015
Background: The study of human leukocytes (HLA) alleles, and haplotype frequencies within populations provide an important source of information for anthropological investigation, organ and hematopoietic stem cell transplantation as well as disease ...
Aroub A.R Al-kaisi, Khalida M. Mousawy, Usama N. Rifat   +2 more
doaj  

Diversity of Calpain-Calpastatin gene frequencies in Brown, Brindle and Jeju Black Hanwoo [PDF]

, 2013
Seung Hwan Lee, Seungchang Kim, Soo‐Hyun Cho, Bong‐Hwan Choi, Aditi Sharma, Dajeong Lim, Chang-Gwan Dang, Sun-Sik Chang, Jaehwan Kim, Moon Suk Ko, Boh-Suck Yang, Hee–Sul Kang   +11 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

The Identification of a Novel, High Frequency Variant in the Cytochrome b Gene in an Isolated Population of a Rare Fish, Spined Loach <i>Cobitis taenia</i>, in England: A Population Worth Protecting?

, 2017
Raheleh Rahbari, K. Tannahill, Catherine Tobin, P. W. J. Robotham, Iain D. Nicholl   +4 more
openalex   +2 more sources

Allele and genotype frequencies of the SOD1 gene polymorphism associated with canine degenerative myelopathy in Belgian Malinois dogs in Greece [PDF]

, 2021
Αντωνία Ματαράγκα, John Ikonomopoulos, G. Zervas, Christos D. Vamvakidis, Nikolaos Tzimotoudis, Ariadne L. Hager‐Theodorides, Maria Gazouli, Antonios Kominakis   +7 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Characteristics of the local distribution of the Y139C resistance gene in Norway rats (Rattus norvegicus) in a focus of resistance in Westphalia, Germany

Julius-Kühn-Archiv, 2011
The Westphalian resistant Norway rat strain is characterised by the possession of the Y139C variant of the vkorc1 gene, and practical resistance occurs in rat infestations at different frequencies to the anticoagulants warfarin, coumatetralyl ...
Klemann, N., Esther, A., Endepols, S.
doaj   +1 more source

Spatial Gene Frequency Waves Under Genotype-Dependent Dispersal. [PDF]

Genetics, 2017
Novak S, Kollár R.
europepmc   +1 more source

Gamma frequency entrainment attenuates amyloid load and modifies microglia

Nature, 2016
Hannah F. Iaccarino, A. Singer, Anthony J. Martorell, A. Rudenko, Fan Gao, Tyler Z Gillingham, Hansruedi Mathys, Jinsoo Seo, Oleg Kritskiy, Fatema Abdurrob, Chinnakkaruppan Adaikkan, Rebecca G. Canter, Richard Rueda, E. Brown, E. Boyden, L. Tsai   +15 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source