Molecular Oncology, EarlyView.B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez +17 more
wiley +1 more source
The landscape of non-reference SINE-VNTR-Alus in amyotrophic lateral sclerosis. [PDF]
Exp Biol Med (Maywood)Pfaff AL, Bubb VJ, Quinn JP, Kõks S.
europepmc +1 more source
High-frequency meiotic gene conversion between repeated genes on nonhomologous chromosomes in yeast. [PDF]
, 1985 Sue Jinks-Robertson, T D Petes
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Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
High-frequency transformation of yeast by plasmids containing the cloned yeast ARG4 gene
, 1979 Chu-Lai Hsiao, John Carbon
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High frequency of clonal immunoglobulin or T cell receptor gene rearrangements in acute myelogenous leukemia expressing terminal deoxyribonucleotidyltransferase. [PDF]
, 1987 Stephanie Seremetis +8 more
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Molecular Oncology, EarlyView.Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen +12 more
wiley +1 more source
Effect of temporal fluctuation of selection coefficient on gene frequency in a population.
, 1975 Naoyuki Takahata, K. Ishii, H. Matsuda
openalex +1 more source
High-frequency conversion to a "fluffy" developmental phenotype in Aspergillus spp. by 5-azacytidine treatment: evidence for involvement of a single nuclear gene. [PDF]
, 1983 Mercedes Tamame +3 more
openalex +1 more source