Results 11 to 20 of about 2,521,918 (64)

Update on Viral Gene Therapy Clinical Trials for Retinal Diseases [PDF]

, 2022
In 2001, the first large animal was successfully treated with a gene therapy that restored its vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness called Leber's congenital amaurosis type 2.
Cheng, Shun-Yun, Punzo, Claudio
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Influência do gene halotano sobre a qualidade da carne suína em dois cruzamentos comerciais [PDF]

, 2009
Mestre em Ciências VeterináriasO objetivo deste trabalho foi avaliar o efeito do gene halotano sobre as características de qualidade da carne suína.
Freitas, Paulo Fernando Alves de
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RNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencing. [PDF]

, 2013
The in vivo accessibility of the chick embryo makes it a favoured model system for experimental developmental biology. Although the range of available techniques now extends to miss-expression of genes through in ovo electroporation, it remains difficult
Bueno i Torrens, David, 1965-, Hernández Hernández, Victor   +1 more
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Association of the AFF3 gene and IL2/IL21 gene region with juvenile idiopathic arthritis [PDF]

, 2010
Recent genetic studies have led to identification of numerous loci that are associated with susceptibility to autoimmune diseases. The strategy of using information from these studies has facilitated the identification of novel juvenile idiopathic ...
S Eyre, J Worthington, X Ke, P Martin, W Thomson, A Hinks, E Flynn, J Packham, A Barton, Martin, P., Barton, A., Gardner-Medwin, J. [CAPS and BSPAR study groups], UKRAG Consortium, Worthington, J., Thomson, W., Flynn, E., Packham, J., Hinks, A., British Society of Paediatric and Adolescent Rheumatology (BSPAR) Study Group, Eyre, S., Ke, X., Childhood Arthritis Prospective Study (CAPS)   +21 more
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Association of the CCR5 gene with juvenile idiopathic arthritis [PDF]

, 2010
The CC chemokine receptor 5 (CCR5) has been shown to be important in the recruitment of T-helper cells to the synovium, where they accumulate, drive the inflammatory process and the consequent synovitis and joint destruction.
Martin, P., BSPAR Study Group, Barton, A., UKRAG Consortium, Worthington, J., Gardner-Medwin, J. [CAPS and BSPAR Study Groups], Thomson, W., W Thomson, Flynn, E., A Hinks, E Flynn, J Packham, Packham, J., Hinks, A., S Eyre, J Worthington, Eyre, S.; id_orcid, Eyre, S., Barton, A.; id_orcid, P Martin, Childhood Arthritis Prospective Study (CAPS), Martin, P.; id_orcid, A Barton   +22 more
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O efeito dos anestésicos inalatórios Halotano e Sevoflurano em um modelo experimental de lesão hepática [PDF]

, 2011
Justificativa e objetivos: A lesão hepática pós-anestesia inalatória ainda é controversa. Estudos sugerem que agentes inalatórios geram uma resposta imune que pode provocar lesões hepáticas.
Medeiros, Susi Heliene Lauz, Soubhia, Andrea Fogaça, Mespaque, Luciane Bicca, Facin, Emilio, Oliveira, Alessandro Menezes de, Montero, Edna Frasson de Souza   +5 more
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Gene Therapy for Fibrodysplasia Ossificans Progressiva: Feasibility and Obstacles [PDF]

, 2022
Fibrodysplasia ossificans progressiva (FOP) is a rare and devastating genetic disease, in which soft connective tissue is converted into heterotopic bone through an endochondral ossification process.
Shim, Jae-Hyuck, Delai, Patricia L R, Madhuri, Vrisha, De Cunto, Carmen L, de Ruiter, Ruben D, Schoenmaker, Ton, Zasloff, Michael, Friedman, Clive S, Gao, Guangping, Cho, Tae-Joon, Morhart, Rolf, Grunwald, Zvi, di Rocco, Maja, Haga, Nobuhiko, de Vries, Teun J, Hsiao, Edward C, Pals, Gerard, Netelenbos, Coen, Diecidue, Robert J, Kaplan, Frederick, Smilde, Bernard J, Scott, Christiaan, Eekhoff, Elisabeth M W, Pignolo, Robert J, Micha, Dimitra   +24 more
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PADRONIZAÇÃO DE UM TESTE DE DIAGNÓSTICO MOLECULAR UTILIZANDO SONDAS TAQMAN® PARA A DETECÇÃO DO GENE DO HALOTANO EM SUÍNOS

, 2014
A hipertermia maligna é uma doença muscular hereditária conhecida como síndrome do estresse dos suínos (PSS), causada por vários fatores como estresse físico, calórico, castração, brigas entre animais, vacinação e, inclusive, a administração do ...
Ledur, Mônica, Ibelli, Adriana Guaratini, Peixoto, Jane De Oliveira, Petry, Bruna, Zanella, Ricardo, Figueiredo, Elsio   +5 more
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Gene Therapy for Allergic Diseases

, 2010
Allergic diseases, such as allergic asthma, allergic rhinitis, atopic dermatitis, conjunctivitis, urticaria, food allergy, and/or anaphylaxis, are associated with the skewing of immune responses towards a T helper 2 ( TH2) phenotype, resulting in ...
莊雅惠;楊曜旭;江伯倫, CHUANG, YA-HUI;YANG, YAO-HSU;CHIANG, BOR-LUEN   +1 more
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Efeitos da infusão contínua de cetamina s(+) em eqüinos anestesiados pelo halotano [PDF]

, 2010
The horse’s blood pressure is susceptible to changes induced by volatile anesthetics. Because of that, the use of anesthesic techniques which keep stable the horse´s blood pressure is essencial.
Santos, Paulo Sérgio Patto dos, Valadão, Carlos, Borges, José Henrique Saraiva, Canola, Júlio Carlos, Dória, Renata Gebara Sampaio, Souza, Adriana Helena de   +5 more
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